Any feedback?
Literature summary extracted from
- Ontogeny of hepatic microsomal 3-hydroxylation of quinine in Adelie Penguins (2004), Comp. Biochem. Physiol. C, 138, 53-58 .
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.14.14.55 | 2-naphthoflavone | about 20% inhibition at 0.05 mM | Pygoscelis adeliae |  |
| 1.14.14.55 | midazolam | about 75% inhibition at 0.05 mM | Pygoscelis adeliae | |
| 1.14.14.55 | troleandomycin | about 10% inhibition at 0.05 mM | Pygoscelis adeliae | |
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 1.14.14.55 | microsome | - |
Pygoscelis adeliae | - |
- |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.14.14.55 | quinine + [reduced NADPH-hemoprotein reductase] + O2 | Pygoscelis adeliae | - |
3-hydroxyquinine + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.14.14.55 | Pygoscelis adeliae | - |
- |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 1.14.14.55 | liver | - |
Pygoscelis adeliae | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.14.14.55 | quinine + [reduced NADPH-hemoprotein reductase] + O2 | - |
Pygoscelis adeliae | 3-hydroxyquinine + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 1.14.14.55 | CYP3A4 | - |
Pygoscelis adeliae |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
