Literature summary extracted from

Brengel, C.; Thomann, A.; Schifrin, A.; Allegretta, G.; Kamal, A.A.M.; Haupenthal, J.; Schnorr, I.; Cho, S.H.; Franzblau, S.G.; Empting, M.; Eberhard, J.; Hartmann, R.W.
Biophysical screening of a focused library for the discovery of CYP121 inhibitors as novel antimycobacterials (2017), ChemMedChem, 12, 1616-1626 .

Application

EC Number	Application	Comment	Organism
1.14.19.70	medicine	CYP121 is a potential target for the treatment of Mycobacterium tuberculosis infections	Mycobacterium tuberculosis
1.14.19.70	pharmacology	CYP121 is a potential target for the treatment of Mycobacterium tuberculosis infections	Mycobacterium tuberculosis

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
1.14.19.70	additional information	biophysical screening procedure employing a focused library of privileged scaffolds, which ultimately lead to the discovery of novel CYP121 inhibitors	Mycobacterium tuberculosis

Organism

EC Number	Organism	UniProt	Comment	Textmining
1.14.19.70	Mycobacterium tuberculosis	P9WPP7	-	-
1.14.19.70	Mycobacterium tuberculosis H37Rv	P9WPP7	-	-

Synonyms

EC Number	Synonyms	Comment	Organism
1.14.19.70	CYP121	-	Mycobacterium tuberculosis

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Release 2023.1 (January 2023)