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Literature summary extracted from

  • Wang, Y.; Zhang, S.; Poetter, M.; Sun, W.; Li, L.; Yang, X.; Jiao, X.; Zhao, Z.K.
    Overexpression of DELTA12-fatty acid desaturase in the oleaginous yeast Rhodosporidium toruloides for production of linoleic acid-rich lipids (2016), Appl. Biochem. Biotechnol., 180, 1497-1507 .
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.14.19.6 recombinant expression in Rhodosporidium toruloides with integration into the genome using Agrobacterium tumefaciens strain AGL1, the recombinnat expression leads to increased production of linoleic acid from oleic acid in the tranformed cells, while no significant decrease in the relative contents of the other fatty acids, namely, C14:0 (myristic acid), C16:0 (palmitic acid), and C16:1 (palmitoleic acid) is observed Fusarium verticillioides
1.14.19.6 recombinant expression of His6-tagged enzyme FADS1 in Rhodosporidium toruloides with integration into the genome using Agrobacterium tumefaciens strain AGL1, the recombinnat expression leads to increased production of linoleic acid from oleic acid in the tranformed cells, while no significant decrease in the relative contents of the other fatty acids, namely, C14:0 (myristic acid), C16:0 (palmitic acid), and C16:1 (palmitoleic acid) is observed Mortierella alpina

Protein Variants

EC Number Protein Variants Comment Organism
1.14.19.6 additional information for improvment of the linoleic acid content in the lipids of Rhodosporidium toruloides, galactose-inducible expression of the gene encoding DELTA12-fatty acid desaturase (FADS) from Mortierella alpina or Fusarium verticillioides by integration of the corresponding expression cassettes into the genome of Rhodosporidium toruloides haploid and diploid strains Mortierella alpina
1.14.19.6 additional information for improvment of the linoleic acid content in the lipids of Rhodosporidium toruloides, galactose-inducible expression of the gene encoding DELTA12-fatty acid desaturase (FADS) from Mortierella alpina or Fusarium verticillioides by integration of the corresponding expression cassettes into the genome of Rhodosporidium toruloides haploid and diploid strains Fusarium verticillioides

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.14.19.6 membrane presence of more than three transmembrane helices in the enzyme Mortierella alpina 16020
-
1.14.19.6 membrane presence of more than three transmembrane helices in the enzyme Fusarium verticillioides 16020
-

Organism

EC Number Organism UniProt Comment Textmining
1.14.19.6 Fusarium verticillioides Q27ZJ7 i.e. Gibberella fujikuroi
-
1.14.19.6 Mortierella alpina
-
-
-

Subunits

EC Number Subunits Comment Organism
1.14.19.6 ? x * 44000, recombinant His6-tagged enzyme, SDS-PAGE Mortierella alpina

Synonyms

EC Number Synonyms Comment Organism
1.14.19.6 delta-12 fatty acid desaturase
-
 Mortierella alpina
1.14.19.6 delta-12 fatty acid desaturase
-
 Fusarium verticillioides
1.14.19.6 FADS1
-
 Mortierella alpina
1.14.19.6 FADS2
-
 Fusarium verticillioides