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Literature summary extracted from

  • Murphy, J.W.; Richmond, R.H.
    Changes to coral health and metabolic activity under oxygen deprivation (2016), PeerJ, 4, e1956 .
    View publication on PubMedView publication on EuropePMC

Activating Compound

EC Number Activating Compound Comment Organism Structure
1.5.1.17 additional information increased activity of alanopine dehydrogenase, ADH, and strombine dehydrogenase, SDH, enzymes in Montipora capitata exposed to prolonged durations of hypoxic conditions Montipora capitata
1.5.1.22 additional information increased activity of alanopine dehydrogenase, ADH, and strombine dehydrogenase, SDH, enzymes in Montipora capitata exposed to prolonged durations of hypoxic conditions Montipora capitata

Application

EC Number Application Comment Organism
1.5.1.17 diagnostics the significant positive relationship between exposure length and enzyme activity of ADH and strombine dehydrogenase, SDH, in Montipora capitata supports the implementation of these enzymes as biomarkers for rapid analysis of hypoxia-induced stress in corals Montipora capitata
1.5.1.22 diagnostics the significant positive relationship between exposure length and enzyme activity of alanopine dehydrogenase, ADH, and SDH in Montipora capitata supports the implementation of these enzymes as biomarkers for rapid analysis of hypoxia-induced stress in corals Montipora capitata

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.5.1.11 L-arginine + pyruvate + NADH + H+ Montipora capitata
-
 N2-(D-1-carboxyethyl)-L-arginine + NAD+ + H2O
-
 ?
1.5.1.17 L-alanine + pyruvate + NADH + H+ Montipora capitata
-
 2,2'-iminodipropanoate + NAD+ + H2O
-
 r
1.5.1.22 glycine + pyruvate + NADH + H+ Montipora capitata the reduction reaction is preferred N-(carboxymethyl)-D-alanine + NAD+ + H2O
-
 r

Organism

EC Number Organism UniProt Comment Textmining
1.5.1.11 Montipora capitata
-
 from Hawaii
-
1.5.1.17 Montipora capitata
-
 from Hawaii
-
1.5.1.22 Montipora capitata
-
 from Hawaii
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.5.1.11 coral nubbin
-
 Montipora capitata
-
1.5.1.17 coral nubbin
-
 Montipora capitata
-
1.5.1.22 coral nubbin
-
 Montipora capitata
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.5.1.11 L-arginine + pyruvate + NADH + H+
-
 Montipora capitata N2-(D-1-carboxyethyl)-L-arginine + NAD+ + H2O
-
 ?
1.5.1.17 L-alanine + pyruvate + NADH + H+
-
 Montipora capitata 2,2'-iminodipropanoate + NAD+ + H2O
-
 r
1.5.1.22 glycine + pyruvate + NADH + H+ the reduction reaction is preferred Montipora capitata N-(carboxymethyl)-D-alanine + NAD+ + H2O
-
 r

Synonyms

EC Number Synonyms Comment Organism
1.5.1.11 ODH
-
 Montipora capitata
1.5.1.17 ADH
-
 Montipora capitata
1.5.1.22 SDH
-
 Montipora capitata

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
1.5.1.11 28
-
 assay at Montipora capitata
1.5.1.17 28
-
 assay at Montipora capitata
1.5.1.22 28
-
 assay at Montipora capitata

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.5.1.11 7.2
-
 assay at Montipora capitata
1.5.1.17 7.2
-
 assay at Montipora capitata
1.5.1.22 7.2
-
 assay at Montipora capitata

Cofactor

EC Number Cofactor Comment Organism Structure
1.5.1.11 NAD+
-
 Montipora capitata
1.5.1.11 NADH
-
 Montipora capitata
1.5.1.17 NAD+
-
 Montipora capitata
1.5.1.17 NADH
-
 Montipora capitata
1.5.1.22 NAD+
-
 Montipora capitata
1.5.1.22 NADH
-
 Montipora capitata

General Information

EC Number General Information Comment Organism
1.5.1.11 additional information chronic nighttime hypoxia does not affect the ODH enzyme activity in corals Montipora capitata
1.5.1.17 metabolism the enzyme activities of opine dehydrogenases, including alanopine dehydrogenase, are increased during anaerobic metabolism in corals under prolonged oxygen deprivation, due to invasive algal overgrowth and oxygen deprivation of wide-spread distributed Montipora capitata in Kaneohe Bay, Oahu, Hawaii Montipora capitata
1.5.1.17 additional information enzyme ADH activity varies significantly with respect to hypoxia treatment type, treatment duration, and interaction between treatment duration and type. The combinatory effect of oxygen deprivation over time had no significant effect on ADH activity. Importantly, control and tank samples display no significant differences over 3 h, 6 h, 1 day, and 3 day times sets, indicating that bubbling within small chambers has no effect on target enzyme activity Montipora capitata
1.5.1.17 physiological function enzyme ADH acts as one of the primary and anaerobic metabolic responses pathways during hypoxia. Montipora capitata increasingly relies upon alanopine dehydrogenase, ADH, and strombine dehydrogenase, SDH, for anaerobic catabolism under low-oxygen conditions Montipora capitata
1.5.1.22 metabolism the enzyme activities of opine dehydrogenases, including strombine dehydrogenase, are increased during anaerobic metabolism in corals under prolonged oxygen deprivation, due to invasive algal overgrowth and oxygen deprivation of wide-spread distributed Montipora capitata in Kaneohe Bay, Oahu, Hawaii Montipora capitata
1.5.1.22 additional information enzyme SDH activity varies significantly with respect to hypoxia treatment type, treatment duration, and interaction between treatment duration and type. Importantly, control and tank samples display no significant differences over 3 h, 6 h, 1 day, and 3 day times sets, indicating that bubbling within small chambers has no effect on target enzyme activity Montipora capitata
1.5.1.22 physiological function enzyme SDH acts as one of the primary and anaerobic metabolic responses pathways during hypoxia. Montipora capitata increasingly relies upon alanopine dehydrogenase, ADH, and strombine dehydrogenase, SDH, for anaerobic catabolism under low-oxygen conditions Montipora capitata