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Literature summary extracted from

  • Murakawa, T.; Hamaguchi, A.; Nakanishi, S.; Kataoka, M.; Nakai, T.; Kawano, Y.; Yamaguchi, H.; Hayashi, H.; Tanizawa, K.; Okajima, T.
    probing the catalytic mechanism of copper amine oxidase from Arthrobacter globiformis with halide ions (2015), J. Biol. Chem., 290, 23094-23109 .
    View publication on PubMedView publication on EuropePMC

Crystallization (Commentary)

EC Number Crystallization (Comment) Organism
1.4.3.21 microdialysis using 1.05 M potassium-sodium tartrate in 25 mM HEPES buffer, pH 6.8 containing 45% (v/v) glycerol Arthrobacter globiformis

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.4.3.21 Br- uncompetitive inhibitor with respect to the substrate amine and noncompetitive inhibitor with respect to dissolved oxygen Arthrobacter globiformis
1.4.3.21 Cl- uncompetitive inhibitor with respect to the substrate amine and noncompetitive inhibitor with respect to dissolved oxygen Arthrobacter globiformis
1.4.3.21 F- uncompetitive inhibitor with respect to the substrate amine and noncompetitive inhibitor with respect to dissolved oxygen Arthrobacter globiformis
1.4.3.21 I- uncompetitive inhibitor with respect to the substrate amine and noncompetitive inhibitor with respect to dissolved oxygen Arthrobacter globiformis

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
1.4.3.21 Cu2+ dependent on Arthrobacter globiformis

Organism

EC Number Organism UniProt Comment Textmining
1.4.3.21 Arthrobacter globiformis P46881
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.4.3.21 2-phenylethylamine + H2O + O2
-
Arthrobacter globiformis phenylacetaldehyde + NH3 + H2O2
-
?
1.4.3.21 ethylamine + H2O + O2
-
Arthrobacter globiformis acetaldehyde + NH3 + H2O2
-
?
1.4.3.21 histamine + H2O + O2
-
Arthrobacter globiformis 1H-imidazol-4-ylacetaldehyde + NH3 + H2O2
-
?

Synonyms

EC Number Synonyms Comment Organism
1.4.3.21 CAO
-
Arthrobacter globiformis
1.4.3.21 Copper amine oxidase
-
Arthrobacter globiformis

Cofactor

EC Number Cofactor Comment Organism Structure
1.4.3.21 L-topaquinone
-
Arthrobacter globiformis