EC Number | Cloned (Comment) | Organism |
---|---|---|
7.2.1.1 | - |
Vibrio cholerae serotype O1 |
EC Number | Protein Variants | Comment | Organism |
---|---|---|---|
7.2.1.1 | G140A | mutation in subunit NrqB, affects ubiquinone reduction and the proper functioning of the sodium pump. Mutation does not not affect the dissociation constant of ubiquinone or inhibitor 2-n-heptyl-4-hydroxyquinoline N-oxide from Na+-NQR and prevents the conformational change involved in ubiquinone binding | Vibrio cholerae serotype O1 |
7.2.1.1 | G141V | mutation in subunit NrqB, affects ubiquinone reduction and the proper functioning of the sodium pump. Mutation does not not affect the dissociation constant of ubiquinone or inhibitor 2-n-heptyl-4-hydroxyquinoline N-oxide from Na+-NQR and prevents the conformational change involved in ubiquinone binding | Vibrio cholerae serotype O1 |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
7.2.1.1 | 2-n-heptyl-4-hydroxyquinoline N-oxide | - |
Vibrio cholerae serotype O1 |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
7.2.1.1 | Vibrio cholerae serotype O1 | A5F5X1 and A5F5X0 and A5F5Y7 and A5F5Y6 and A5F5Y3 and A5F5Y4 | A5F5X1: subunit NqrA, A5F5X0: subunit NqrB, A5F5Y7: subunit NqrC, A5F5Y6: subunit NqrD; A5F5Y3: subunit NqrE, A5F5Y4: subunit NqrF. The enzyme consists of six subunits encoded by the NQR operon. | - |
7.2.1.1 | Vibrio cholerae serotype O1 ATCC 39541 | A5F5X1 and A5F5X0 and A5F5Y7 and A5F5Y6 and A5F5Y3 and A5F5Y4 | A5F5X1: subunit NqrA, A5F5X0: subunit NqrB, A5F5Y7: subunit NqrC, A5F5Y6: subunit NqrD; A5F5Y3: subunit NqrE, A5F5Y4: subunit NqrF. The enzyme consists of six subunits encoded by the NQR operon. | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
7.2.1.1 | additional information | the site of ubiquinone reduction is conformationally coupled to the NqrB subunit, which also hosts the final cofactor in the electron transport chain, riboflavin | Vibrio cholerae serotype O1 | ? | - |
? | |
7.2.1.1 | additional information | the site of ubiquinone reduction is conformationally coupled to the NqrB subunit, which also hosts the final cofactor in the electron transport chain, riboflavin | Vibrio cholerae serotype O1 ATCC 39541 | ? | - |
? |