EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
1.6.5.5 | Colchicine | noncompetitive with respect to 9,10-phenanthrenequinone and 1,2-naphthoquinone, uncompetitive with respect to NADPH. Binding of colchicine occurs at or close to the NADPH binding site | Camelus sp. |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.6.5.5 | Camelus sp. | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
1.6.5.5 | lens | - |
Camelus sp. | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.6.5.5 | 2 1,2-naphthoquinone + NADPH + H+ | - |
Camelus sp. | 2 1,2-naphthosemiquinone + NADP+ | - |
? | |
1.6.5.5 | 2 9,10-phenanthrenequinone + NADPH + H+ | - |
Camelus sp. | 2 9,10-phenanthrenesemiquinone + NADP+ | - |
? |
EC Number | IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|---|
1.6.5.5 | 0.0015 | - |
pH not specified in the publication, temperature not specified in the publication | Camelus sp. | Colchicine |