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Literature summary extracted from

  • Zhao, L.; Liu, W.; Chen, X.; Wang, M.; Feng, J.; Wu, Q.; Zhu, D.
    Effect of residue Y76 on co-enzyme specificity of meso-diaminopimelate dehydrogenase from Symbiobacterium thermophilum (2015), Chin. J. Biotechnol., 31, 1108-1118 .
    View publication on PubMed

Protein Variants

EC Number Protein Variants Comment Organism
1.4.1.16 R35S/R36V the mutations significantly lower the specific activity toward NADP+ compared to the wild type enzyme. The mutant enzyme favors NAD+ over NADP+ Symbiobacterium thermophilum

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.4.1.16 meso-2,6-diaminoheptanedioate + H2O + NADP+ Symbiobacterium thermophilum
-
 L-2-amino-6-oxoheptanedioate + NH3 + NADPH + H+
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.4.1.16 Symbiobacterium thermophilum Q67PI3
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.4.1.16 meso-2,6-diaminoheptanedioate + H2O + NADP+
-
 Symbiobacterium thermophilum L-2-amino-6-oxoheptanedioate + NH3 + NADPH + H+
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.4.1.16 DAPDH
-
 Symbiobacterium thermophilum
1.4.1.16 meso-diaminopimelate dehydrogenase
-
 Symbiobacterium thermophilum

Cofactor

EC Number Cofactor Comment Organism Structure
1.4.1.16 NADP+
-
 Symbiobacterium thermophilum