Literature summary extracted from

Kutanovas, S.; Karvelis, L.; Vaitekunas, J.; Stankeviciute, J.; Gasparaviciute, R.; Meskys, R.
Isolation and characterization of novel pyridine dicarboxylic acid-degrading microorganisms (2016), Chemija, 27, 74-83 .

No PubMed abstract available

Cloned(Commentary)

EC Number	Cloned (Comment)	Organism
1.13.11.9	phylogenetic analysis	Cupriavidus campinensis

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
1.13.11.9	2,5-dihydroxypyridine + O2	Cupriavidus campinensis	-	N-formylmaleamic acid	-	?
1.13.11.9	2,5-dihydroxypyridine + O2	Cupriavidus campinensis 23K8	-	N-formylmaleamic acid	-	?

Organism

EC Number	Organism	UniProt	Comment	Textmining
1.13.11.9	Cupriavidus campinensis	-	i.e. Wautersia campinensis	-
1.13.11.9	Cupriavidus campinensis 23K8	-	i.e. Wautersia campinensis	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
1.13.11.9	cell culture	pyridine-2,6-dicarboxylic acid- and pyridine-2,3-dicarboxylic acid-induced strain 23K8 cells. The cells do not grow on pyridine-2,5-dicarboxylic acid	Cupriavidus campinensis	-

Specific Activity [micromol/min/mg]

EC Number	Specific Activity Minimum [µmol/min/mg]	Specific Activity Maximum [µmol/min/mg]	Comment	Organism
1.13.11.9	0.13	-	pyridine-2,6-dicarboxylic acid-induced cells of strain 23K8, pH 7.2, 30°C	Cupriavidus campinensis

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
1.13.11.9	2,5-dihydroxypyridine + O2	-	Cupriavidus campinensis	N-formylmaleamic acid	-	?
1.13.11.9	2,5-dihydroxypyridine + O2	-	Cupriavidus campinensis 23K8	N-formylmaleamic acid	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
1.13.11.9	2,5-dihydroxypyridine dioxygenase	-	Cupriavidus campinensis

Temperature Optimum [°C]

EC Number	Temperature Optimum [°C]	Temperature Optimum Maximum [°C]	Comment	Organism
1.13.11.9	30	-	assay at	Cupriavidus campinensis

pH Optimum

EC Number	pH Optimum Minimum	pH Optimum Maximum	Comment	Organism
1.13.11.9	7.2	-	assay at	Cupriavidus campinensis

General Information

EC Number	General Information	Comment	Organism
1.13.11.9	metabolism	the enzyme catalyzes the last step of putative pathway of pyridine-2,3-dicarboxylic acid oxidation in Cupriavidus campinensis 23K8	Cupriavidus campinensis

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Release 2023.1 (January 2023)