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Literature summary extracted from

  • Zhou, C.; Liu, Y.; Li, X.; Zou, J.; Zou, S.
    DNA N6-methyladenine demethylase ALKBH1 enhances osteogenic differentiation of human MSCs (2016), Bone Res., 4, 16033 .
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.14.11.51 N6-methyladenine in DNA + 2-oxoglutarate + O2 Homo sapiens
-
 adenine in DNA + formaldehyde + succinate + CO2
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.14.11.51 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.14.11.51 mesenchymal stem cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.11.51 N6-methyladenine in DNA + 2-oxoglutarate + O2
-
 Homo sapiens adenine in DNA + formaldehyde + succinate + CO2
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.14.11.51 ALKBH1
-
 Homo sapiens

Expression

EC Number Organism Comment Expression
1.14.11.51 Homo sapiens enzyme expression in human mesenchymal stem cells is upregulated during osteogenic induction up

General Information

EC Number General Information Comment Organism
1.14.11.51 malfunction enzyme-depleted mesenchymal stem cells exhibit a restricted capacity for bone formation in vivo Homo sapiens
1.14.11.51 physiological function enzyme overexpression enhances osteoblastic differentiation of mesenchymal stem cells Homo sapiens