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Literature summary extracted from

  • Cervelli, M.; Angelucci, E.; Stano, P.; Leboffe, L.; Federico, R.; Antonini, G.; Mariottini, P.; Polticelli, F.
    The Glu216/Ser218 pocket is a major determinant of spermine oxidase substrate specificity (2014), Biochem. J., 461, 453-459 .
    View publication on PubMed

Protein Variants

EC Number Protein Variants Comment Organism
1.5.3.16 E216L/S218A mutation E216L/S218A endows the enzyme with N1-acetylspermine oxidase activity Mus musculus

Organism

EC Number Organism UniProt Comment Textmining
1.5.3.16 Mus musculus Q99K82
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.5.3.16 N1-acetylspermine + O2 + H2O mutation E216L/S218A endows the enzyme with N1-acetylspermine oxidase activity Mus musculus spermidine + 3-acetamidopropanal + H2O2
-
 ?
1.5.3.16 spermine + O2 + H2O
-
 Mus musculus spermidine + 3-aminopropanal + H2O2
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.5.3.16 MmSMO
-
 Mus musculus