Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Siebels, I.; Droese, S.
    Charge translocation by mitochondrial NADH ubiquinone oxidoreductase (complex I) from Yarrowia lipolytica measured on solid-supported membranes (2016), Biochem. Biophys. Res. Commun., 479, 277-282 .
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
7.1.1.2 expression in Yarrowia lipolytica Yarrowia lipolytica

Inhibitors

EC Number Inhibitors Comment Organism Structure
7.1.1.2 2-n-decyl-quinazolin-4-yl-amine transport is completely sensitive to 2-n-decyl-quinazolin-4-yl-amine Yarrowia lipolytica
7.1.1.2 5-(N-ethyl-N-isopropyl)amiloride inhibits of complex I and increases the membrane conductivity Yarrowia lipolytica
7.1.1.2 Zn2+ 0.1 mM, reversible stabilization of inactive form Yarrowia lipolytica

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
7.1.1.2 membrane
-
 Yarrowia lipolytica 16020
-

Organism

EC Number Organism UniProt Comment Textmining
7.1.1.2 Yarrowia lipolytica Q9UUU0 NUGM, 30-kDa subunit of complex I
-
7.1.1.2 Yarrowia lipolytica PIPO Q9UUU0 NUGM, 30-kDa subunit of complex I
-

Purification (Commentary)

EC Number Purification (Comment) Organism
7.1.1.2 solubilized by n-dodecyl-beta-D-maltoside Yarrowia lipolytica

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
7.1.1.2 NADH + n-decylubiquinone + 5 H+[side1]
-
 Yarrowia lipolytica NAD+ + n-decylubiquinol + 4 H+[side2]
-
 ?
7.1.1.2 NADH + n-decylubiquinone + 5 H+[side1]
-
 Yarrowia lipolytica PIPO NAD+ + n-decylubiquinol + 4 H+[side2]
-
 ?