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Literature summary extracted from

  • Dreifke, M.; Fried, D.; Brieler, F.; Froeba, M.
    Kinetic investigations of 6-phosphogluconate dehydrogenase confined in mesoporous silica (2016), J. Mol. Catal. B, 132, 5-15.
No PubMed abstract available

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.1.1.44 0.0034
-
 NADP+ free enzyme, at pH 7.5 and 25°C Geobacillus stearothermophilus
1.1.1.44 0.0822
-
 6-phospho-D-gluconate free enzyme, at pH 7.5 and 25°C Geobacillus stearothermophilus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.1.1.44 57000
-
 2 * 57000, SDS-PAGE Geobacillus stearothermophilus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.1.1.44 6-phospho-D-gluconate + NADP+ Geobacillus stearothermophilus
-
 D-ribulose 5-phosphate + CO2 + NADPH + H+
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.44 Geobacillus stearothermophilus
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.44 6-phospho-D-gluconate + NADP+
-
 Geobacillus stearothermophilus D-ribulose 5-phosphate + CO2 + NADPH + H+
-
 ?

Subunits

EC Number Subunits Comment Organism
1.1.1.44 homodimer 2 * 57000, SDS-PAGE Geobacillus stearothermophilus

Synonyms

EC Number Synonyms Comment Organism
1.1.1.44 6-phosphogluconate dehydrogenase
-
 Geobacillus stearothermophilus
1.1.1.44 6PGDH
-
 Geobacillus stearothermophilus

Turnover Number [1/s]

EC Number Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
1.1.1.44 22.1
-
 NADP+ free enzyme, at pH 7.5 and 25°C Geobacillus stearothermophilus
1.1.1.44 22.1
-
 6-phospho-D-gluconate free enzyme, at pH 7.5 and 25°C Geobacillus stearothermophilus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.1.1.44 7.5
-
-
 Geobacillus stearothermophilus

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.44 NADP+ dependent on Geobacillus stearothermophilus

pI Value

EC Number Organism Comment pI Value Maximum pI Value
1.1.1.44 Geobacillus stearothermophilus isoelectric focusing
-
 6.5