BRENDA - Enzyme Database show

Nicotinamide is a specific inhibitor of dark-operative protochlorophyllide oxidoreductase, a nitrogenase-like enzyme, from Rhodobacter capsulatus

Nomata, J.; Kondo, T.; Itoh, S.; Fujita, Y.; FEBS Lett. 587, 3142-3147 (2013)

Data extracted from this reference:

Inhibitors
EC Number
Inhibitors
Commentary
Organism
Structure
1.3.1.33
nicotinamide
inhibits DPOR activity by blocking the electron transfer from the L-protein to the NB-protein subunit
Rhodobacter capsulatus
Natural Substrates/ Products (Substrates)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
1.3.1.33
protochlorophyllide + NADPH + H+
Rhodobacter capsulatus
-
chlorophyllide a + NADP+
-
-
?
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
1.3.1.33
Rhodobacter capsulatus
-
-
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
1.3.1.33
protochlorophyllide + NADPH + H+
-
740446
Rhodobacter capsulatus
chlorophyllide a + NADP+
-
-
-
?
Cofactor
EC Number
Cofactor
Commentary
Organism
Structure
1.3.1.33
NADPH
-
Rhodobacter capsulatus
1.3.1.33
[4Fe-4S]-center
-
Rhodobacter capsulatus
Cofactor (protein specific)
EC Number
Cofactor
Commentary
Organism
Structure
1.3.1.33
NADPH
-
Rhodobacter capsulatus
1.3.1.33
[4Fe-4S]-center
-
Rhodobacter capsulatus
Inhibitors (protein specific)
EC Number
Inhibitors
Commentary
Organism
Structure
1.3.1.33
nicotinamide
inhibits DPOR activity by blocking the electron transfer from the L-protein to the NB-protein subunit
Rhodobacter capsulatus
Natural Substrates/ Products (Substrates) (protein specific)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
1.3.1.33
protochlorophyllide + NADPH + H+
Rhodobacter capsulatus
-
chlorophyllide a + NADP+
-
-
?
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
1.3.1.33
protochlorophyllide + NADPH + H+
-
740446
Rhodobacter capsulatus
chlorophyllide a + NADP+
-
-
-
?