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Literature summary extracted from

  • Rafiqul, I.S.; Sakinah, A.M.; Zularisam, A.W.
    Inhibition by toxic compounds in the hemicellulosic hydrolysates on the activity of xylose reductase from Candida tropicalis (2015), Biotechnol. Lett., 37, 191-196.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.1.1.431 5-hydroxymethylfurfural
-
 Candida tropicalis
1.1.1.431 acetic acid
-
 Candida tropicalis
1.1.1.431 furfural
-
 Candida tropicalis
1.1.1.431 Tannic acid
-
 Candida tropicalis

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.431 Candida tropicalis
-
-
-
1.1.1.431 Candida tropicalis IFO 0618
-
-
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.1.1.431 11.16
-
 pH 7.0, 25°C Candida tropicalis

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.431 D-xylose + NADPH + H+
-
 Candida tropicalis xylitol + NADP+
-
 ?
1.1.1.431 D-xylose + NADPH + H+
-
 Candida tropicalis IFO 0618 xylitol + NADP+
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
1.1.1.431 25
-
-
 Candida tropicalis

Temperature Range [°C]

EC Number Temperature Minimum [°C] Temperature Maximum [°C] Comment Organism
1.1.1.431 40
-
 enzyme is fully active up to 40°C Candida tropicalis

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.431 NADPH enzyme is specific for NADPH Candida tropicalis

IC50 Value

EC Number IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
1.1.1.431 additional information
-
 IC50 value 0.4 g/l, pH 7.0, 25°C Candida tropicalis 5-hydroxymethylfurfural
1.1.1.431 additional information
-
 IC50 value 11 g/l, pH 7.0, 25°C Candida tropicalis acetic acid
1.1.1.431 additional information
-
 IC50 value 2.3 g/l, pH 7.0, 25°C Candida tropicalis furfural
1.1.1.431 additional information
-
 IC50 value 6.4 g/l, pH 7.0, 25°C Candida tropicalis Tannic acid