Literature summary extracted from

Grosshennig, S.; Ischebeck, T.; Gibhardt, J.; Busse, J.; Feussner, I.; Stuelke, J.
Hydrogen sulfide is a novel potential virulence factor of Mycoplasma pneumoniae: characterization of the unusual cysteine desulfurase/desulfhydrase HapE (2016), Mol. Microbiol., 100, 42-54.

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
2.8.1.7	L-cysteine + acceptor	Mycoplasma pneumoniae	-	L-alanine + S-sulfanyl-acceptor	-	?

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.8.1.7	Mycoplasma pneumoniae	-	-	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2.8.1.7	L-cysteine + acceptor	-	Mycoplasma pneumoniae	L-alanine + S-sulfanyl-acceptor	-	?
2.8.1.7	additional information	HapE is a bifunctional enzyme which has both the cysteine desulfurase activity to produce alanine and the cysteine desulfhydrase activity to produce pyruvate and hydrogen sulfide	Mycoplasma pneumoniae	?	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
2.8.1.7	hAPE	-	Mycoplasma pneumoniae

General Information

EC Number	General Information	Comment	Organism
2.8.1.7	physiological function	the enzyme is a potential virulence factor of Mycoplasma pneumoniae being responsible for haemolysis	Mycoplasma pneumoniae

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Release 2023.1 (January 2023)