EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.10.2 | ATP + a [protein]-L-tyrosine | Mus musculus | - |
ADP + a [protein]-L-tyrosine phosphate | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.7.10.2 | Mus musculus | P35991 | - |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.10.2 | ATP + a [protein]-L-tyrosine | - |
Mus musculus | ADP + a [protein]-L-tyrosine phosphate | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.7.10.2 | Bruton's tyrosine kinase | - |
Mus musculus |
2.7.10.2 | Btk | - |
Mus musculus |
EC Number | General Information | Comment | Organism |
---|---|---|---|
2.7.10.2 | malfunction | enzyme-deficiency leads to a reduction in mature peripheral B cells. Enzyme-deficient mice fail to respond to immunization with type 2 thymus-independent antigens, and accordingly, peripheral B cells from these animals are unresponsive to B cell receptor crosslinking | Mus musculus |
2.7.10.2 | physiological function | the enzyme is essential for B cell activation and differentiation | Mus musculus |