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Literature summary extracted from

  • Felux, A.K.; Denger, K.; Weiss, M.; Cook, A.M.; Schleheck, D.
    Paracoccus denitrificans PD1222 utilizes hypotaurine via transamination followed by spontaneous desulfination to yield acetaldehyde and, finally, acetate for growth (2013), J. Bacteriol., 195, 2921-2930.
    View publication on PubMedView publication on EuropePMC

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.6.1.77 50000
-
 x * 50000, SDS-PAGE Paracoccus denitrificans

Organism

EC Number Organism UniProt Comment Textmining
2.6.1.77 Paracoccus denitrificans A1B9Z3
-
-
2.6.1.77 Paracoccus denitrificans Pd 1222 A1B9Z3
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.6.1.77 hypotaurine + pyruvate
-
 Paracoccus denitrificans 2-aminoethanesulfinic acid + L-alanine product 2-aminoethanesulfinic acid desulfinates spontaneously to acetaldehyde and sulfite ?
2.6.1.77 hypotaurine + pyruvate
-
 Paracoccus denitrificans Pd 1222 2-aminoethanesulfinic acid + L-alanine product 2-aminoethanesulfinic acid desulfinates spontaneously to acetaldehyde and sulfite ?
2.6.1.77 taurine + 2-oxobutanoate about 50% of the activity with taurine Paracoccus denitrificans 2-sulfoacetaldehyde + 2-aminobutanoate product 2-sulfoacetaldehyde desulfinates spontaneously to acetaldehyde and sulfite ?
2.6.1.77 taurine + 2-oxobutanoate about 50% of the activity with taurine Paracoccus denitrificans Pd 1222 2-sulfoacetaldehyde + 2-aminobutanoate product 2-sulfoacetaldehyde desulfinates spontaneously to acetaldehyde and sulfite ?

Subunits

EC Number Subunits Comment Organism
2.6.1.77 ? x * 50000, SDS-PAGE Paracoccus denitrificans

Synonyms

EC Number Synonyms Comment Organism
2.6.1.77 HPA
-
 Paracoccus denitrificans
2.6.1.77 hypotaurine-inducible hypotaurine:pyruvate aminotransferase
-
 Paracoccus denitrificans
2.6.1.77 Pden_4273
-
 Paracoccus denitrificans

General Information

EC Number General Information Comment Organism
2.6.1.77 physiological function degradation pathway for hypotaurine in strain PD1222 can be depicted as follows: The aminotransferase converts hypotaurine to sulfinoacetaldehyde, which desulfinates spontaneously to acetaldehyde and sulfite. An inducible aldehyde dehydrogenase oxidizes acetaldehyde to yield acetate, which is metabolized, and sulfite, which is excreted Paracoccus denitrificans