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Literature summary extracted from

  • Asai, D.; Murata, M.; Toita, R.; Kawano, T.; Nakashima, H.; Kang, J.H.
    Role of amino acid residues surrounding the phosphorylation site in peptide substrates of G protein-coupled receptor kinase 2 (GRK2) (2016), Amino Acids, 48, 2875-2880.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.11.15 ATP + [beta-adrenergic receptor] Homo sapiens
-
 ADP + phospho-[beta-adrenergic receptor]
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.11.15 Homo sapiens
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.11.15 ATP + Ac-DEMEFTEAESNMN-NH2 highly specific substrate with phosphorylation sites at Thr409 and Ser413 Homo sapiens ADP + Ac-DEMEFpTEAESNMN-NH2
-
 ?
2.7.11.15 ATP + Ac-DEMEFTHAESNMN-NH2
-
 Homo sapiens ADP + Ac-DEMEFpTHAESNMN-NH2
-
 ?
2.7.11.15 ATP + Ac-DEMKFTEAESNMN-NH2
-
 Homo sapiens ADP + Ac-DEMKFpTEAESNMN-NH2
-
 ?
2.7.11.15 ATP + Ac-DEMKFTHAESNMN-NH2
-
 Homo sapiens ADP + Ac-DEMKFpTHAESNMN-NH2
-
 ?
2.7.11.15 ATP + Ac-DEMSFTEAESNMN-NH2
-
 Homo sapiens ADP + Ac-DEMSFpTEAESNMN-NH2
-
 ?
2.7.11.15 ATP + Ac-DEMSFTHAEANMN-NH2
-
 Homo sapiens ADP + Ac-DEMSFpTHAEANMN-NH2
-
 ?
2.7.11.15 ATP + Ac-EEMEFSEAEANMN-NH2
-
 Homo sapiens ADP + Ac-EEMEFpSEAEANMN-NH2
-
 ?
2.7.11.15 ATP + Ac-EEMEFSEEAANMN-NH2
-
 Homo sapiens ADP + Ac-EEMEFpSEEAANMN-NH2
-
 ?
2.7.11.15 ATP + Ac-EEMEFTEVEANMN-NH2
-
 Homo sapiens ADP + Ac-EEMEFpTEVEANMN-NH2
-
 ?
2.7.11.15 ATP + [beta-adrenergic receptor]
-
 Homo sapiens ADP + phospho-[beta-adrenergic receptor]
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.11.15 G protein-coupled receptor kinase 2
-
 Homo sapiens
2.7.11.15 GRK2
-
 Homo sapiens