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Literature summary extracted from

  • Klumpp, S.; Hermesmeier, J.; Selke, D.; Bechmann, G.; Van den Brulle, J.; Weidner, G.; Scharm, B.; Gussow, D.; Baumeister, R.; Kellner, R.; Krieglstein, J.
    Protein histidine phosphatase: A novel enzyme with potency for neuronal signaling (2003), J. Cereb. Blood Flow Metab., 22, 1420-1424.
    View publication on PubMed

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.9.1.3 Mg2+ 10 mM Mg2+ are used in assay conditions Mus musculus
3.9.1.3 Mg2+ 10 mM Mg2+ are used in assay conditions Rattus norvegicus
3.9.1.3 Mg2+ 10 mM Mg2+ are used in assay conditions Caenorhabditis elegans
3.9.1.3 Mg2+ 10 mM Mg2+ are used in assay conditions Oryctolagus cuniculus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.9.1.3 14000
-
 x * 14000, SDS-PAGE Mus musculus
3.9.1.3 14000
-
 x * 14000, SDS-PAGE Rattus norvegicus
3.9.1.3 14000
-
 x * 14000, SDS-PAGE Caenorhabditis elegans
3.9.1.3 14000
-
 x * 14000, SDS-PAGE Oryctolagus cuniculus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.9.1.3 a [CheA protein]-N-phospho-L-histidine + H2O Mus musculus
-
 a [CheA protein]-L-histidine + phosphate
-
 ?
3.9.1.3 a [CheA protein]-N-phospho-L-histidine + H2O Rattus norvegicus
-
 a [CheA protein]-L-histidine + phosphate
-
 ?
3.9.1.3 a [CheA protein]-N-phospho-L-histidine + H2O Caenorhabditis elegans
-
 a [CheA protein]-L-histidine + phosphate
-
 ?
3.9.1.3 a [CheA protein]-N-phospho-L-histidine + H2O Oryctolagus cuniculus
-
 a [CheA protein]-L-histidine + phosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.9.1.3 Caenorhabditis elegans
-
-
-
3.9.1.3 Mus musculus
-
-
-
3.9.1.3 Oryctolagus cuniculus P83468
-
-
3.9.1.3 Rattus norvegicus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.9.1.3 ammonium sulfate precipitation, Blue Sepharose column chromatography, and Superdex 75 gel filtration Mus musculus
3.9.1.3 ammonium sulfate precipitation, Blue Sepharose column chromatography, and Superdex 75 gel filtration Rattus norvegicus
3.9.1.3 ammonium sulfate precipitation, Blue Sepharose column chromatography, and Superdex 75 gel filtration Caenorhabditis elegans
3.9.1.3 ammonium sulfate precipitation, Blue Sepharose column chromatography, and Superdex 75 gel filtration Oryctolagus cuniculus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.9.1.3 brain
-
 Mus musculus
-
3.9.1.3 brain
-
 Rattus norvegicus
-
3.9.1.3 brain
-
 Oryctolagus cuniculus
-
3.9.1.3 heart
-
 Mus musculus
-
3.9.1.3 heart
-
 Rattus norvegicus
-
3.9.1.3 heart
-
 Oryctolagus cuniculus
-
3.9.1.3 kidney
-
 Mus musculus
-
3.9.1.3 kidney
-
 Rattus norvegicus
-
3.9.1.3 kidney
-
 Oryctolagus cuniculus
-
3.9.1.3 liver
-
 Mus musculus
-
3.9.1.3 liver
-
 Rattus norvegicus
-
3.9.1.3 liver
-
 Oryctolagus cuniculus
-
3.9.1.3 neuron
-
 Caenorhabditis elegans
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.9.1.3 a [CheA protein]-N-phospho-L-histidine + H2O
-
 Mus musculus a [CheA protein]-L-histidine + phosphate
-
 ?
3.9.1.3 a [CheA protein]-N-phospho-L-histidine + H2O
-
 Rattus norvegicus a [CheA protein]-L-histidine + phosphate
-
 ?
3.9.1.3 a [CheA protein]-N-phospho-L-histidine + H2O
-
 Caenorhabditis elegans a [CheA protein]-L-histidine + phosphate
-
 ?
3.9.1.3 a [CheA protein]-N-phospho-L-histidine + H2O
-
 Oryctolagus cuniculus a [CheA protein]-L-histidine + phosphate
-
 ?

Subunits

EC Number Subunits Comment Organism
3.9.1.3 ? x * 14000, SDS-PAGE Mus musculus
3.9.1.3 ? x * 14000, SDS-PAGE Rattus norvegicus
3.9.1.3 ? x * 14000, SDS-PAGE Caenorhabditis elegans
3.9.1.3 ? x * 14000, SDS-PAGE Oryctolagus cuniculus

Synonyms

EC Number Synonyms Comment Organism
3.9.1.3 PHP
-
 Mus musculus
3.9.1.3 PHP
-
 Rattus norvegicus
3.9.1.3 PHP
-
 Caenorhabditis elegans
3.9.1.3 PHP
-
 Oryctolagus cuniculus
3.9.1.3 protein histidine phosphatase
-
 Mus musculus
3.9.1.3 protein histidine phosphatase
-
 Rattus norvegicus
3.9.1.3 protein histidine phosphatase
-
 Caenorhabditis elegans
3.9.1.3 protein histidine phosphatase
-
 Oryctolagus cuniculus