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Literature summary extracted from

  • Arjunan, P.; Wang, J.; Nemeria, N.S.; Reynolds, S.; Brown, I.; Chandrasekhar, K.; Calero, G.; Jordan, F.; Furey, W.
    Novel binding motif and new flexibility revealed by structural analyses of a pyruvate dehydrogenase-dihydrolipoyl acetyltransferase subcomplex from the Escherichia coli pyruvate dehydrogenase multienzyme complex (2014), J. Biol. Chem., 289, 30161-30176.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.3.1.12 expressed in Escherichia coli AG1 cells Escherichia coli

Crystallization (Commentary)

EC Number Crystallization (Comment) Organism
2.3.1.12 E1p-E2p didomain subcomplex, sitting drop vapor diffusion method, using 20% (w/v) PEG 3350, 0.2% (w/v) NaN3, and 0.2 M ammonium tartrate dibasic buffer (pH 6.35) Escherichia coli

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.3.1.12 65959
-
 x * 65959, calculated from amino acid sequence Escherichia coli

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.3.1.12 acetyl-CoA + enzyme N6-(dihydrolipoyl)lysine Escherichia coli
-
 CoA + enzyme N6-(S-acetyldihydrolipoyl)lysine
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.12 Escherichia coli P06959
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.3.1.12
-
 Escherichia coli

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.12 acetyl-CoA + enzyme N6-(dihydrolipoyl)lysine
-
 Escherichia coli CoA + enzyme N6-(S-acetyldihydrolipoyl)lysine
-
 ?

Subunits

EC Number Subunits Comment Organism
2.3.1.12 ? x * 65959, calculated from amino acid sequence Escherichia coli

Synonyms

EC Number Synonyms Comment Organism
2.3.1.12 dihydrolipoyl acetyltransferase
-
 Escherichia coli
2.3.1.12 pyruvate dehydrogenase complex component E2p
-
 Escherichia coli