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Literature summary extracted from

  • Gerken, T.A.; Revoredo, L.; Thome, J.J.; Tabak, L.A.; Vester-Christensen, M.B.; Clausen, H.; Gahlay, G.K.; Jarvis, D.L.; Johnson, R.W.; Moniz, H.A.; Moremen, K.
    The lectin domain of the polypeptide GalNAc transferase family of glycosyltransferases (ppGalNAc Ts) acts as a switch directing glycopeptide substrate glycosylation in an N- or C-terminal direction, further controlling mucin type O-glycosylation (2013), J. Biol. Chem., 288, 19900-19914.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.4.1.41 expressed in Sf9 insect cells Bos taurus
2.4.1.41 expressed in Sf9 insect cells Pichia pastoris G115 cells Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.41 Bos taurus
-
-
-
2.4.1.41 Homo sapiens
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.4.1.41 Ni-NTA-agarose column chromatography and MonoQ column chromatography Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.41 UDP-N-acetyl-alpha-D-galactosamine + polypeptide GPIV preferred substrate Bos taurus UDP + N-acetyl-alpha-D-galactosaminyl-polypeptide GPIV
-
 ?
2.4.1.41 UDP-N-acetyl-alpha-D-galactosamine + polypeptide GPIV preferred substrate for isoforms ppGalNAc T2, T5, T13, T14, and T16 Homo sapiens UDP + N-acetyl-alpha-D-galactosaminyl-polypeptide GPIV
-
 ?
2.4.1.41 UDP-N-acetyl-alpha-D-galactosamine + polypeptide GPIV-C
-
 Homo sapiens UDP + N-acetyl-alpha-D-galactosaminyl-polypeptide GPIV-C
-
 ?
2.4.1.41 UDP-N-acetyl-alpha-D-galactosamine + polypeptide GPV
-
 Bos taurus UDP + N-acetyl-alpha-D-galactosaminyl-polypeptide GPV
-
 ?
2.4.1.41 UDP-N-acetyl-alpha-D-galactosamine + polypeptide GPV preferred substrate for isoforms ppGalNAc T3, T5, T6, T13, and T16 Homo sapiens UDP + N-acetyl-alpha-D-galactosaminyl-polypeptide GPV
-
 ?
2.4.1.41 UDP-N-acetyl-alpha-D-galactosamine + polypeptide GPV-C
-
 Homo sapiens UDP + N-acetyl-alpha-D-galactosaminyl-polypeptide GPV-C
-
 ?
2.4.1.41 UDP-N-acetyl-alpha-D-galactosamine + polypeptide GPV-C
-
 Bos taurus UDP + N-acetyl-alpha-D-galactosaminyl-polypeptide GPV-C
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.4.1.41 polyppetide GalNAc transferase
-
 Homo sapiens
2.4.1.41 polyppetide GalNAc transferase
-
 Bos taurus
2.4.1.41 ppGalNAc T1 isoform Bos taurus
2.4.1.41 ppGalNAc T13 isoform Homo sapiens
2.4.1.41 ppGalNAc T16 isoform Homo sapiens
2.4.1.41 ppGalNAc T2 isoform Homo sapiens
2.4.1.41 ppGalNAc T3 isoform Homo sapiens
2.4.1.41 ppGalNAc T5 isoform Homo sapiens
2.4.1.41 ppGalNAc T6 isoform Homo sapiens