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Literature summary extracted from

  • Sharma, S.; Sun, X.; Agarwal, S.; Rafikov, R.; Dasarathy, S.; Kumar, S.; Black, S.
    Role of carnitine acetyl transferase in regulation of nitric oxide signaling in pulmonary arterial endothelial cells (2013), Int. J. Mol. Sci., 14, 255-272.
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.3.1.7 acyl-CoA + L-carnitine Homo sapiens
-
 CoA + O-acylcarnitine
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.7 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.7 pulmonary artery endothelial cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.7 acyl-CoA + L-carnitine
-
 Homo sapiens CoA + O-acylcarnitine
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.3.1.7 carnitine acetyl transferase
-
 Homo sapiens
2.3.1.7 CRAT
-
 Homo sapiens

General Information

EC Number General Information Comment Organism
2.3.1.7 malfunction silencing the CrAT gene disrupts cellular carnitine homeostasis, reduces the expression of mitochondrial superoxide dismutase 2 and results in an increase in oxidative stress within the mitochondrion Homo sapiens