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Literature summary extracted from

  • Wan, X.; Sato, H.; Miyaji, H.; McDaniel, J.M.; Wang, Y.; Kaneko, E.; Gibson, B.; Mehta-DSouza, P.; Chen, Y.; Dozmorov, M.; Miller, L.P.; Goodman, J.; Sun, Z.; Xia, L.
    Fucosyltransferase VII improves the function of selectin ligands on cord blood hematopoietic stem cells (2013), Glycobiology, 23, 1184-1191.
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.4.1.65 GDP-beta-L-fucose + beta-D-galactosyl-(1->3)-N-acetyl-D-glucosaminyl-R Mus musculus
-
 GDP + beta-D-galactosyl-(1->3)-[alpha-L-fucosyl-(1->4)]-N-acetyl-beta-D-glucosaminyl-R
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.65 Mus musculus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.1.65 culture condition:CD34+ cell
-
 Mus musculus
-
2.4.1.65 hematopoietic cell
-
 Mus musculus
-
2.4.1.65 hematopoietic stem cell
-
 Mus musculus
-
2.4.1.65 umbilical cord blood cell
-
 Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.65 GDP-beta-L-fucose + beta-D-galactosyl-(1->3)-N-acetyl-D-glucosaminyl-R
-
 Mus musculus GDP + beta-D-galactosyl-(1->3)-[alpha-L-fucosyl-(1->4)]-N-acetyl-beta-D-glucosaminyl-R
-
 ?
2.4.1.65 additional information isoform FUT7 is able to synthesize both di- and tri-fucosylated structures from monofucosylated precursors but preferentially fucosylates the distal N-acetylglucosamine within a polylactosamine chain Mus musculus ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.4.1.65 alpha1,3 fucosyltransferase VII
-
 Mus musculus
2.4.1.65 FUT7
-
 Mus musculus

General Information

EC Number General Information Comment Organism
2.4.1.65 physiological function the enzyme improves the function of selectin ligands on cord blood hematopoietic stem cells Mus musculus