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Literature summary extracted from

  • Zheng, J.; Luo, Z.; Zhu, Q.; Chen, Q.; Gong, Y.
    Molecular characterization, Tissue distribution and kinetic analysis of carnitine palmitoyltransferase I in juvenile yellow catfish Pelteobagrus fulvidraco (2013), Genomics, 101, 195-203.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.1.21 malonyl-CoA complete inhibition at 0.05 mM; complete inhibition at 0.05 mM; complete inhibition at 0.05 mM; complete inhibition at 0.05 mM Tachysurus fulvidraco

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.3.1.21 0.0127
-
 palmitoyl-CoA enzyme from intestine, at pH 8.0 and 37°C Tachysurus fulvidraco
2.3.1.21 0.0137
-
 palmitoyl-CoA enzyme from heart, at pH 8.0 and 37°C Tachysurus fulvidraco
2.3.1.21 0.014
-
 palmitoyl-CoA enzyme from muscle, at pH 8.0 and 37°C Tachysurus fulvidraco
2.3.1.21 0.0159
-
 palmitoyl-CoA enzyme from liver, at pH 8.0 and 37°C Tachysurus fulvidraco
2.3.1.21 0.0167
-
 palmitoyl-CoA enzyme from spleen, at pH 8.0 and 37°C Tachysurus fulvidraco
2.3.1.21 0.69
-
 L-carnitine enzyme from spleen, at pH 8.0 and 37°C Tachysurus fulvidraco
2.3.1.21 0.93
-
 L-carnitine enzyme from muscle, at pH 8.0 and 37°C Tachysurus fulvidraco
2.3.1.21 0.98
-
 L-carnitine enzyme from heart, at pH 8.0 and 37°C Tachysurus fulvidraco
2.3.1.21 1.16
-
 L-carnitine enzyme from liver, at pH 8.0 and 37°C Tachysurus fulvidraco
2.3.1.21 1.34
-
 L-carnitine enzyme from intestine, at pH 8.0 and 37°C Tachysurus fulvidraco

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.3.1.21 outer mitochondrial membrane
-
 Tachysurus fulvidraco
-
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.3.1.21 palmitoyl-CoA + L-carnitine Tachysurus fulvidraco
-
 CoA + L-palmitoylcarnitine
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.21 Tachysurus fulvidraco M4H3I4 yellow catfish
-
2.3.1.21 Tachysurus fulvidraco M4H3S7 yellow catfish
-
2.3.1.21 Tachysurus fulvidraco M4H428 yellow catfish
-
2.3.1.21 Tachysurus fulvidraco M4H4E4 yellow catfish
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.21 heart highest activity in liver and heart Tachysurus fulvidraco
-
2.3.1.21 intestine
-
 Tachysurus fulvidraco
-
2.3.1.21 juvenile
-
 Tachysurus fulvidraco
-
2.3.1.21 liver highest activity in liver and heart Tachysurus fulvidraco
-
2.3.1.21 mesenteric adipose tissue
-
 Tachysurus fulvidraco
-
2.3.1.21 spleen lowest activity in muscle and spleen Tachysurus fulvidraco
-
2.3.1.21 white muscle lowest activity in muscle and spleen Tachysurus fulvidraco
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.21 palmitoyl-CoA + L-carnitine
-
 Tachysurus fulvidraco CoA + L-palmitoylcarnitine
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.3.1.21 carnitine palmitoyltransferase I
-
 Tachysurus fulvidraco
2.3.1.21 CPT Ialpha1a isoform Tachysurus fulvidraco
2.3.1.21 CPT Ialpha1b isoform Tachysurus fulvidraco
2.3.1.21 CPT Ialpha2a isoform Tachysurus fulvidraco
2.3.1.21 CPT Ibeta isoform Tachysurus fulvidraco