EC Number | Application | Comment | Organism |
---|---|---|---|
2.4.1.90 | medicine | enzyme expression is an independent prognostic factor for poor survival of neuroblastoma patients | Homo sapiens |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.4.1.90 | UDP-alpha-D-galactose + N-acetyl-D-glucosamine | Homo sapiens | - |
UDP + N-acetyllactosamine | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.4.1.90 | Homo sapiens | P15291 | - |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
2.4.1.90 | neuroblastoma cell | - |
Homo sapiens | - |
2.4.1.90 | SH-SY5Y cell | - |
Homo sapiens | - |
2.4.1.90 | SK-N-DZ cell | - |
Homo sapiens | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.4.1.90 | UDP-alpha-D-galactose + N-acetyl-D-glucosamine | - |
Homo sapiens | UDP + N-acetyllactosamine | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.4.1.90 | B4GALT3 | - |
Homo sapiens |
2.4.1.90 | beta-1,4-galactosyltransferase III | - |
Homo sapiens |
EC Number | General Information | Comment | Organism |
---|---|---|---|
2.4.1.90 | physiological function | enzyme overexpression increases migration, invasion, and tumor growth of neuroblastoma cells, increases lactosamine glycans on beta1-integrin, increases expression of mature beta1-integrin via delayed degradation, and enhances phosphorylation of focal adhesion kinase | Homo sapiens |