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Literature summary extracted from

  • Holm, D.K.; Petersen, L.M.; Klitgaard, A.; Knudsen, P.B.; Jarczynska, Z.D.; Nielsen, K.F.; Gotfredsen, C.H.; Larsen, T.O.; Mortensen, U.H.
    Molecular and chemical characterization of the biosynthesis of the 6-MSA-derived meroterpenoid yanuthone D in Aspergillus niger (2014), Chem. Biol., 21, 519-529.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.3.1.165 expression in Aspergillus nidulans Aspergillus niger

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.165 Aspergillus niger G3Y419
-
-
2.3.1.165 Aspergillus niger ATCC 1015 G3Y419
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.165 acetyl-CoA + 3 malonyl-CoA + NADPH + H+
-
 Aspergillus niger 6-methylsalicylate + 4 CoA + 3 CO2 + NADP+ + H2O
-
 ?
2.3.1.165 acetyl-CoA + 3 malonyl-CoA + NADPH + H+
-
 Aspergillus niger ATCC 1015 6-methylsalicylate + 4 CoA + 3 CO2 + NADP+ + H2O
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.3.1.165 ASPNIDRAFT_44965
-
 Aspergillus niger
2.3.1.165 PKS48
-
 Aspergillus niger
2.3.1.165 YanA
-
 Aspergillus niger

General Information

EC Number General Information Comment Organism
2.3.1.165 physiological function enzyme is involved in synthesis of yanuthones D and E Aspergillus niger