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Literature summary extracted from

  • Bradley, R.M.; Marvyn, P.M.; Aristizabal Henao, J.J.; Mardian, E.B.; George, S.; Aucoin, M.G.; Stark, K.D.; Duncan, R.E.
    Acylglycerophosphate acyltransferase 4 (AGPAT4) is a mitochondrial lysophosphatidic acid acyltransferase that regulates brain phosphatidylcholine, phosphatidylethanolamine, and phosphatidylinositol levels (2015), Biochim. Biophys. Acta, 1851, 1566-1576.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.3.1.51 expressed in HEK-293 or Sf9 insect cells Mus musculus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.3.1.51 mitochondrion
-
 Mus musculus 5739
-
2.3.1.51 outer mitochondrial membrane
-
 Mus musculus
-
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.3.1.51 44000
-
 x * 44000, SDS-PAGE Mus musculus

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.51 Mus musculus Q8K4X7
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.51 brain
-
 Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.51 oleoyl-CoA + 1-arachidonoyl-sn-glycerol 3-phosphate
-
 Mus musculus CoA + 1-arachidonoyl-2-oleoyl-sn-glycerol 3-phosphate
-
 ?
2.3.1.51 oleoyl-CoA + 1-oleoyl-sn-glycerol 3-phosphate
-
 Mus musculus CoA + 1,2-dioleoyl-sn-glycerol 3-phosphate
-
 ?

Subunits

EC Number Subunits Comment Organism
2.3.1.51 ? x * 44000, SDS-PAGE Mus musculus

Synonyms

EC Number Synonyms Comment Organism
2.3.1.51 acyl-CoA:lysophospholipid acyltransferase
-
 Mus musculus
2.3.1.51 acylglycerophosphate acyltransferase 4
-
 Mus musculus
2.3.1.51 AGPAT4
-
 Mus musculus
2.3.1.51 LPAATdelta
-
 Mus musculus
2.3.1.51 lysophosphatidic acid acyltransferase
-
 Mus musculus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.3.1.51 7.4
-
-
 Mus musculus

General Information

EC Number General Information Comment Organism
2.3.1.51 metabolism the enzyme specifically supports synthesis of brain phosphatidylinositol, phosphatidylcholine, and phosphatidylethanolamine Mus musculus