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Literature summary extracted from

  • Faris, R.; Fan, Y.Y.; De Angulo, A.; Chapkin, R.S.; deGraffenried, L.A.; Jolly, C.A.
    Mitochondrial glycerol-3-phosphate acyltransferase-1 is essential for murine CD4(+) T cell metabolic activation (2014), Biochim. Biophys. Acta, 1842, 1475-1482.
    View publication on PubMedView publication on EuropePMC

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.3.1.15 mitochondrion
-
 Mus musculus 5739
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.3.1.15 acyl-CoA + sn-glycerol 3-phosphate Mus musculus
-
 CoA + lysophosphatidic acid
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.15 Mus musculus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.15 helper T-lymphocyte CD4+ Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.15 acyl-CoA + sn-glycerol 3-phosphate
-
 Mus musculus CoA + lysophosphatidic acid
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.3.1.15 glycerol-3-phosphate acyltransferase-1
-
 Mus musculus
2.3.1.15 GPAT-1
-
 Mus musculus

General Information

EC Number General Information Comment Organism
2.3.1.15 malfunction enzyme deficiency results in altered or dysfunctional mitochondria Mus musculus
2.3.1.15 physiological function the enzyme is essential for the response to the increased metabolic demands associated with T cell activation Mus musculus