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Literature summary extracted from

  • Qi, Y.; Li, Y.; Bao, J.J.
    Development of a capillary electrophoresis method for analyzing adenosine deaminase and purine nucleoside phosphorylase and its application in inhibitor screening (2016), Anal. Biochem., 506, 31-44.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.4.2.1 additional information the enzyme is not inhibited by extracts of Hedyotis diffusa, orange peel, Scutellaria baicalensis, Solanum nigrum, Rhizoma Chuanxiong, Prunella vulgaris, Dendranthema indicum, or Paclitaxel. The natural extract of Angelica sinensis exhibits 8.59% inhibition of enzyme activity Homo sapiens

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.4.2.1 0.79
-
 Inosine pH and temperature not specified in the publication Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
2.4.2.1 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.2.1 erythrocyte
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.2.1 inosine + phosphate
-
 Homo sapiens hypoxanthine + alpha-D-ribose 1-phosphate
-
 r

Synonyms

EC Number Synonyms Comment Organism
2.4.2.1 PNP
-
 Homo sapiens
2.4.2.1 purine nucleoside phosphorylase
-
 Homo sapiens

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.4.2.1 7.4
-
-
 Homo sapiens