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Literature summary extracted from

  • Lartigue, C.; Lebaudy, A.; Blanchard, A.; El Yacoubi, B.; Rose, S.; Grosjean, H.; Douthwaite, S.
    The flavoprotein Mcap0476 (RlmFO) catalyzes m5U1939 modification in Mycoplasma capricolum 23SrRNA (2014), Nucleic Acids Res., 42, 8073-8082.
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.1.1.190 S-adenosyl-L-methionine + uracil1939 in 23S rRNA Mycoplasma capricolum
-
 S-adenosyl-L-homocysteine + 5-methyluracil1939 in 23S rRNA
-
 ?
2.1.1.190 S-adenosyl-L-methionine + uracil1939 in 23S rRNA Mycoplasma capricolum ATCC 27343
-
 S-adenosyl-L-homocysteine + 5-methyluracil1939 in 23S rRNA
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.1.1.B117 Mycoplasma capricolum Q2SS13
-
-
2.1.1.B117 Mycoplasma capricolum ATCC 27343 Q2SS13
-
-
2.1.1.190 Mycoplasma capricolum Q2SS13
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.1.1.B117 5,10-methylentetrahydrofolate + uracil1939 in 23S rRNA + FADH2
-
 Mycoplasma capricolum tetrahydrofolate + 5-methyluracil1939 in 23S rRNA + FAD
-
 ?
2.1.1.B117 5,10-methylentetrahydrofolate + uracil1939 in 23S rRNA + FADH2
-
 Mycoplasma capricolum ATCC 27343 tetrahydrofolate + 5-methyluracil1939 in 23S rRNA + FAD
-
 ?
2.1.1.B117 additional information no substrates: tRNA Mycoplasma capricolum ?
-
 ?
2.1.1.B117 additional information no substrates: tRNA Mycoplasma capricolum ATCC 27343 ?
-
 ?
2.1.1.190 S-adenosyl-L-methionine + uracil1939 in 23S rRNA
-
 Mycoplasma capricolum S-adenosyl-L-homocysteine + 5-methyluracil1939 in 23S rRNA
-
 ?
2.1.1.190 S-adenosyl-L-methionine + uracil1939 in 23S rRNA
-
 Mycoplasma capricolum ATCC 27343 S-adenosyl-L-homocysteine + 5-methyluracil1939 in 23S rRNA
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.1.1.B117 Mcap0476
-
 Mycoplasma capricolum
2.1.1.B117 TrmFO 1
-
 Mycoplasma capricolum
2.1.1.190 Mcap0476
-
 Mycoplasma capricolum
2.1.1.190 RlmFO rRNA large subunit methyltransferase, folate-dependent Mycoplasma capricolum

Cofactor

EC Number Cofactor Comment Organism Structure
2.1.1.190 FAD dependent on Mycoplasma capricolum
2.1.1.190 folate dependent on Mycoplasma capricolum