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Literature summary extracted from
- BACE1 activity regulates cell surface contactin-2 levels (2014), Mol. Neurodegener., 9, 004.
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.4.23.46 | Cricetulus griseus | - |
- |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.4.23.46 | CHO cell | - |
Cricetulus griseus | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.4.23.46 | contactin-2 + H2O | substrate is a GPI-anchored cell adhesion molecule | Cricetulus griseus | ? | mouse and human contactin-2 are physiological substrates for BACE1. BACE1-mediated contactin-2 cleavage tightly regulates the surface expression of contactin-2 in neuronal cells | ? |  |
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Release 2023.1 (January 2023)
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