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Literature summary extracted from

  • Li, S.; Zhang, G.; Yuan, Y.; Wang, C.; Gao, W.; Deng, C.; Lu, L.; Hu, Z.
    Three homologous genes encoding functional DELTA8-sphingolipid desaturase in Populus tomentosa (2014), Genes Genomics, 36, 293-301.
No PubMed abstract available

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.14.19.18 expressed in Saccharomyces cerevisiae Populus tomentosa
1.14.19.29 expressed in Saccharomyces cerevisiae Populus tomentosa

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.14.19.29 (4R)-4-hydroxysphinganine ceramide + ferrocytochrome b5 + O2 + H+ Populus tomentosa
-
 (4R,8E)-4-hydroxysphing-8-enine ceramide + ferricytochrome b5 + H2O
-
 ?
1.14.19.29 (4R)-4-hydroxysphinganine ceramide + ferrocytochrome b5 + O2 + H+ Populus tomentosa
-
 (4R,8Z)-4-hydroxysphing-8-enine ceramide + ferricytochrome b5 + H2O
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.14.19.18 Populus tomentosa W8DT12
-
-
1.14.19.18 Populus tomentosa W8DTJ8
-
-
1.14.19.29 Populus tomentosa
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.14.19.18 leaf
-
 Populus tomentosa
-
1.14.19.18 root
-
 Populus tomentosa
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.19.18 C18-phytosphingenine + ferrocytochrome b5 + O2 + H+
-
 Populus tomentosa (8Z)-C18-phytosphingenine + (8E)-C18-phytosphingenine + ferricytochrome b5 + H2O
-
 ?
1.14.19.29 (4R)-4-hydroxysphinganine ceramide + ferrocytochrome b5 + O2 + H+
-
 Populus tomentosa (4R,8E)-4-hydroxysphing-8-enine ceramide + ferricytochrome b5 + H2O
-
 ?
1.14.19.29 (4R)-4-hydroxysphinganine ceramide + ferrocytochrome b5 + O2 + H+
-
 Populus tomentosa (4R,8Z)-4-hydroxysphing-8-enine ceramide + ferricytochrome b5 + H2O
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.14.19.18 D8A gene name, isoform Populus tomentosa
1.14.19.18 D8B gene name, isoform Populus tomentosa
1.14.19.18 DELTA8-sphingolipid desaturase
-
 Populus tomentosa
1.14.19.29 DELTA8-sphingolipid desaturase
-
 Populus tomentosa

Cofactor

EC Number Cofactor Comment Organism Structure
1.14.19.18 cytochrome b5
-
 Populus tomentosa
1.14.19.29 cytochrome b5
-
 Populus tomentosa

General Information

EC Number General Information Comment Organism
1.14.19.18 physiological function transgenic yeasts expressing isoform D8A exhibits enhanced aluminum tolerance Populus tomentosa
1.14.19.18 physiological function transgenic yeasts expressing isoform D8B exhibits enhanced aluminum tolerance Populus tomentosa
1.14.19.29 physiological function the enzyme contributes to aluminum tolerance Populus tomentosa