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Literature summary extracted from
- Inorganic pyrophosphatases: one substrate, three mechanisms (2013), FEBS Lett., 587, 1863-1869.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.6.1.1 | aminomethylenediphosphonate | - |
Thermotoga maritima |  |
| 3.6.1.1 | aminomethylenediphosphonate | - |
Vigna radiata | |
| 3.6.1.1 | fluoride | - |
Thermotoga maritima | |
| 3.6.1.1 | fluoride | - |
Vigna radiata | |
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 3.6.1.1 | membrane | - |
Vigna radiata | 16020 | - |
| 3.6.1.1 | membrane | - |
Thermotoga maritima | 16020 | - |
Metals/Ions
| EC Number | Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.6.1.1 | Mg2+ | required | Vigna radiata | |
| 3.6.1.1 | Mg2+ | required | Thermotoga maritima | |
| 3.6.1.1 | Mn2+ | activates | Vigna radiata | |
| 3.6.1.1 | Mn2+ | activates | Thermotoga maritima | |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.6.1.1 | diphosphate + H2O | Vigna radiata | - |
2 phosphate | - |
? | |
| 3.6.1.1 | diphosphate + H2O | Thermotoga maritima | - |
2 phosphate | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.6.1.1 | Thermotoga maritima | - |
- |
- |
| 3.6.1.1 | Vigna radiata | - |
- |
- |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.6.1.1 | diphosphate + H2O | - |
Vigna radiata | 2 phosphate | - |
? | |
| 3.6.1.1 | diphosphate + H2O | - |
Thermotoga maritima | 2 phosphate | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 3.6.1.1 | inorganic pyrophosphatase | - |
Vigna radiata |
| 3.6.1.1 | inorganic pyrophosphatase | - |
Thermotoga maritima |
| 3.6.1.1 | M-PPase | - |
Vigna radiata |
| 3.6.1.1 | M-PPase | - |
Thermotoga maritima |
| 3.6.1.1 | membrane-integral pyrophosphatase | - |
Vigna radiata |
| 3.6.1.1 | membrane-integral pyrophosphatase | - |
Thermotoga maritima |
General Information
| EC Number | General Information | Comment | Organism |
|---|---|---|---|
| 3.6.1.1 | physiological function | the membrane-integral enzyme uses binding of diphosphate to drive pumping H+ | Vigna radiata |
| 3.6.1.1 | physiological function | the membrane-integral enzyme uses binding of diphosphate to drive pumping Na+ | Thermotoga maritima |
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