EC Number | Application | Comment | Organism |
---|---|---|---|
3.5.1.1 | medicine | the enzyme is an important drug in the treatment of childhood acute lymphoblastic leukemia | Escherichia coli |
EC Number | Crystallization (Comment) | Organism |
---|---|---|
3.5.1.1 | mutant enzyme D90E, hanging drop vapor diffusion method, using 25% PEG MME 550, 100 mM MES pH 6.5, 10 mM ZnSO4 or 30% (w/v) PEG MME 550, 100 mM bicine pH 9.0, 100 mM NaCl or 100 mM HEPES pH 7.5, saturated solution of tribasic sodium citrate mixed with buffer, at citrate:buffer ratio of 9:1 | Escherichia coli |
EC Number | Protein Variants | Comment | Organism |
---|---|---|---|
3.5.1.1 | D90E | active site mutation | Escherichia coli |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
3.5.1.1 | periplasm | - |
Escherichia coli | - |
- |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
3.5.1.1 | Zn2+ | contains zinc | Escherichia coli |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.5.1.1 | L-asparagine + H2O | Escherichia coli | - |
L-aspartate + NH3 | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.5.1.1 | Escherichia coli | P00805 | - |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.5.1.1 | L-asparagine + H2O | - |
Escherichia coli | L-aspartate + NH3 | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
3.5.1.1 | L-asparaginase type II | - |
Escherichia coli |