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Literature summary extracted from
- Inactivation of sterol DELTA5,6-desaturase attenuates virulence in Candida albicans (2005), Antimicrob. Agents Chemother., 49, 3646-3651.
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.14.19.20 | Candida albicans | O93875 | isolates C43, C655, C673, and C410 | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.14.19.20 | 14-methylfecosterol + ferrocytochrome b5 + O2 + H+ | - |
Candida albicans | 14-methylergosta-5,8,24(28)-trien-3beta-ol + ferricytochrome b5 + H2O | - |
? |  |
| 1.14.19.20 | ergosta-7,22-dien-3beta-ol + ferrocytochrome b5 + O2 + H+ | - |
Candida albicans | ergosterol + ferricytochrome b5 + 2 H2O | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 1.14.19.20 | Erg3p | - |
Candida albicans |
| 1.14.19.20 | sterol DELTA5,6-desaturase | - |
Candida albicans |
Cofactor
| EC Number | Cofactor | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.14.19.20 | cytochrome b5 | - |
Candida albicans |
General Information
| EC Number | General Information | Comment | Organism |
|---|---|---|---|
| 1.14.19.20 | malfunction | inactivation of sterol DELTA5,6-desaturase attenuates virulence in Candida albicans | Candida albicans |
| 1.14.19.20 | metabolism | the enzyme is involved in ergosterol synthesis | Candida albicans |
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Release 2023.1 (January 2023)
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