EC Number | Cloned (Comment) | Organism |
---|---|---|
3.5.1.98 | recombinant expression of His-tagged enzyme | Alcaligenes sp. |
3.5.1.98 | recombinant expression of His-tagged isozyme HDAC8 | Homo sapiens |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
3.5.1.98 | 2,2,3,3,4,4,5,5,6,6,7,7-dodecafluorooctanedioic acid hydroxyamide phenylamide | - |
Alcaligenes sp. | |
3.5.1.98 | 2,2,3,3,4,4,5,5,6,6,7,7-dodecafluorooctanedioic acid hydroxyamide phenylamide | - |
Homo sapiens | |
3.5.1.98 | additional information | enzyme binding mechanisms, overview | Alcaligenes sp. | |
3.5.1.98 | additional information | enzyme binding mechanisms, overview; enzyme binding mechanisms, overview; enzyme binding mechanisms, overview | Homo sapiens | |
3.5.1.98 | N-hydroxy-4-{[5-(propan-2-yl)naphthalene-1-sulfonyl]amino}butanamide | - |
Alcaligenes sp. | |
3.5.1.98 | N-hydroxy-4-{[5-(propan-2-yl)naphthalene-1-sulfonyl]amino}butanamide | - |
Homo sapiens | |
3.5.1.98 | N-hydroxy-5-{[5-(propan-2-yl)naphthalene-1-sulfonyl]amino}pentanamide | - |
Alcaligenes sp. | |
3.5.1.98 | N-hydroxy-5-{[5-(propan-2-yl)naphthalene-1-sulfonyl]amino}pentanamide | - |
Homo sapiens | |
3.5.1.98 | N-hydroxy-6-{[5-(propan-2-yl)naphthalene-1-sulfonyl]amino}hexanamide | - |
Alcaligenes sp. | |
3.5.1.98 | N-hydroxy-6-{[5-(propan-2-yl)naphthalene-1-sulfonyl]amino}hexanamide | - |
Homo sapiens | |
3.5.1.98 | N-hydroxy-7-{[5-(propan-2-yl)naphthalene-1-sulfonyl]amino}heptanamide | - |
Alcaligenes sp. | |
3.5.1.98 | N-hydroxy-7-{[5-(propan-2-yl)naphthalene-1-sulfonyl]amino}heptanamide | - |
Homo sapiens | |
3.5.1.98 | N-hydroxy-8-{[5-(propan-2-yl)naphthalene-1-sulfonyl]amino}octanamide | - |
Alcaligenes sp. | |
3.5.1.98 | N-hydroxy-8-{[5-(propan-2-yl)naphthalene-1-sulfonyl]amino}octanamide | - |
Homo sapiens | |
3.5.1.98 | N-hydroxy-N~3~-[5-(propan-2-yl)naphthalene-1-sulfonyl]-beta-alaninamide | - |
Alcaligenes sp. | |
3.5.1.98 | N-hydroxy-N~3~-[5-(propan-2-yl)naphthalene-1-sulfonyl]-beta-alaninamide | - |
Homo sapiens | |
3.5.1.98 | suberoylanilide hydroxamic acid | - |
Alcaligenes sp. | |
3.5.1.98 | suberoylanilide hydroxamic acid | complete inhibition; complete inhibition | Homo sapiens | |
3.5.1.98 | suberoylanilide trifluoromethylketone | - |
Alcaligenes sp. | |
3.5.1.98 | suberoylanilide trifluoromethylketone | - |
Homo sapiens | |
3.5.1.98 | trichostatin A | - |
Alcaligenes sp. | |
3.5.1.98 | trichostatin A | - |
Homo sapiens |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
3.5.1.98 | additional information | - |
additional information | enzyme kinetic calculations, overview | Alcaligenes sp. | |
3.5.1.98 | additional information | - |
additional information | enzyme kinetic calculations, overview | Homo sapiens |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.5.1.98 | Alcaligenes sp. | Q70I53 | i.e. Bordetella sp. strain FB188 | - |
3.5.1.98 | Alcaligenes sp. DSM 11172 | Q70I53 | i.e. Bordetella sp. strain FB188 | - |
3.5.1.98 | Homo sapiens | Q13547 | isozyme HDAC1 | - |
3.5.1.98 | Homo sapiens | Q9BY41 | isozyme HDAC8 | - |
3.5.1.98 | Homo sapiens | Q9UBN7 | isozyme HDAC6 | - |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
3.5.1.98 | commercial preparation | - |
Homo sapiens | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.5.1.98 | Boc-acetyl-Lys-7-amido-4-methylcoumarin + H2O | - |
Homo sapiens | Boc-acetyl-Lys + 7-amino-4-methylcoumarin | - |
? | |
3.5.1.98 | Boc-trifluoroacetyl-Lys-7-amido-4-methylcoumarin + H2O | - |
Homo sapiens | Boc-trifluoroacetyl-Lys + 7-amino-4-methylcoumarin | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
3.5.1.98 | deacetylase-like amidohydrolase | - |
Alcaligenes sp. |
3.5.1.98 | FB188 HDAH | - |
Alcaligenes sp. |
3.5.1.98 | HDAC1 | - |
Homo sapiens |
3.5.1.98 | HDAC6 | - |
Homo sapiens |
3.5.1.98 | HDAC8 | - |
Homo sapiens |
3.5.1.98 | HDAH | - |
Alcaligenes sp. |
EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|---|
3.5.1.98 | 25 | - |
assay at | Alcaligenes sp. |
3.5.1.98 | 25 | - |
assay at | Homo sapiens |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
3.5.1.98 | 8 | - |
assay at | Alcaligenes sp. |
3.5.1.98 | 8 | - |
assay at | Homo sapiens |
EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|---|
3.5.1.98 | additional information | - |
additional information | inhibition kinetic calculations, Kd values, detailed overview | Alcaligenes sp. | |
3.5.1.98 | additional information | - |
additional information | inhibition kinetic calculations, Kd values, detailed overview | Homo sapiens |