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Literature summary extracted from

  • Garbe, J.; Sjoegren, J.; Cosgrave, E.F.; Struwe, W.B.; Bober, M.; Olin, A.I.; Rudd, P.M.; Collin, M.
    EndoE from Enterococcus faecalis hydrolyzes the glycans of the biofilm inhibiting protein lactoferrin and mediates growth (2014), PLoS ONE, 9, e91035.
    View publication on PubMedView publication on EuropePMC

Protein Variants

EC Number Protein Variants Comment Organism
3.2.1.96 E186Q the mutant has an active beta domain but inactive alpha domain and shows no activity with lactoferrin Enterococcus faecalis
3.2.1.96 E662Q the mutant has N active alpha domain but inactive beta domain and shows activity towards lactoferrin Enterococcus faecalis

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.2.1.96 N-glycosylated immunoglobulin G + H2O Enterococcus faecalis
-
 ?
-
 ?
3.2.1.96 N-glycosylated immunoglobulin G + H2O Enterococcus faecalis OG1RF
-
 ?
-
 ?
3.2.1.96 N-glycosylated lactoferrin + H2O Enterococcus faecalis
-
 ?
-
 ?
3.2.1.96 N-glycosylated lactoferrin + H2O Enterococcus faecalis OG1RF
-
 ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.2.1.96 Enterococcus faecalis
-
-
-
3.2.1.96 Enterococcus faecalis OG1RF
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.2.1.96 N-glycosylated immunoglobulin G + H2O
-
 Enterococcus faecalis ?
-
 ?
3.2.1.96 N-glycosylated immunoglobulin G + H2O
-
 Enterococcus faecalis OG1RF ?
-
 ?
3.2.1.96 N-glycosylated lactoferrin + H2O
-
 Enterococcus faecalis ?
-
 ?
3.2.1.96 N-glycosylated lactoferrin + H2O
-
 Enterococcus faecalis OG1RF ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.2.1.96 endo-beta-N-acetylglucosaminidase
-
 Enterococcus faecalis
3.2.1.96 endoE
-
 Enterococcus faecalis

General Information

EC Number General Information Comment Organism
3.2.1.96 physiological function endo-beta-N-acetylglucosaminidase EndoE from Enterococcus faecalis hydrolyzes the glycans of the biofilm inhibiting protein lactoferrin and mediates growth Enterococcus faecalis