EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
3.4.22.53 | Ca2+ | activated by Ca2+ | Danio rerio |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.4.22.53 | Danio rerio | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
3.4.22.53 | brain | - |
Danio rerio | - |
3.4.22.53 | glioblastoma cell | - |
Danio rerio | - |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
3.4.22.53 | calpain 2 | - |
Danio rerio |
EC Number | General Information | Comment | Organism |
---|---|---|---|
3.4.22.53 | malfunction | knockdown of calpain 2 results in a 2.9fold decrease in the invasion of human glioblastoma cells in zebrafish brain. Calpain 2 knockdown cells demonstrate a 2.3fold lower area of dispersal compared with control cells | Danio rerio |
3.4.22.53 | physiological function | calpain 2 is required for the invasion of glioblastoma cells in the living zebrafish brain microenvironment | Danio rerio |