Literature summary extracted from

Turpeinen, H.; Oksanen, A.; Kivinen, V.; Kukkurainen, S.; Uusimaeki, A.; Raemet, M.; Parikka, M.; Hytoenen, V.P.; Nykter, M.; Pesu, M.
Proprotein convertase subtilisin/kexin type 7 (PCSK7) is essential for the zebrafish development and bioavailability of transforming growth factor beta1a (TGFbeta1a) (2013), J. Biol. Chem., 288, 36610-36623.

Cloned(Commentary)

EC Number	Cloned (Comment)	Organism
3.4.21.B27	gene pcsk7, DNA and amino acid sequence determination and analysis, sequence comparison,expression analysis	Danio rerio

Organism

EC Number	Organism	UniProt	Comment	Textmining
3.4.21.B27	Danio rerio	F1R440	gene pcsk7	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
3.4.21.B27	larva	-	Danio rerio	-
3.4.21.B27	additional information	the enzyme is ubiquitously expressed and evident already during the early development, enzyme expression during the first week of fish development and in several tissues, overview	Danio rerio	-

Synonyms

EC Number	Synonyms	Comment	Organism
3.4.21.B27	PCSK7	-	Danio rerio
3.4.21.B27	proprotein convertase subtilisin/kexin type 7	-	Danio rerio

General Information

EC Number	General Information	Comment	Organism
3.4.21.B27	malfunction	inhibiting the enzyme in zebrafish results in various developmental defects and dysregulation of gene expressions, phenotypes, overview	Danio rerio
3.4.21.B27	additional information	homology structure modeling, overview	Danio rerio
3.4.21.B27	physiological function	the enzyme is essential for zebrafish development and regulates the expression and proteolytic cleavage of transforming growth factor beta1a	Danio rerio

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Release 2023.1 (January 2023)