EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
3.4.21.7 | urokinase-type plasminogen activator | converts plasminogen bound to a plasminogen receptor into plasmin | Homo sapiens |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
3.4.21.7 | 6-aminohexanoate | - |
Homo sapiens | |
3.4.21.7 | Aedes aegypti trypsin inhibitor | - |
Homo sapiens | |
3.4.21.7 | alpha-antiplasmin | potent inhibitor | Homo sapiens | |
3.4.21.7 | amyloid precursor-like protein 2 | - |
Homo sapiens | |
3.4.21.7 | Aprotinin | - |
Homo sapiens | |
3.4.21.7 | bdellin | - |
Homo sapiens | |
3.4.21.7 | bikazin salivary inhibitor | - |
Homo sapiens | |
3.4.21.7 | bikunin | - |
Homo sapiens | |
3.4.21.7 | chicken liver trypsin inhibitor | - |
Homo sapiens | |
3.4.21.7 | CU-2010 | potent inhibitpr | Homo sapiens | |
3.4.21.7 | D-Ile-Phe-Lys-CH2Cl | - |
Homo sapiens | |
3.4.21.7 | DX-1000 | - |
Homo sapiens | |
3.4.21.7 | infestin | - |
Homo sapiens | |
3.4.21.7 | KD1-L17R | - |
Homo sapiens | |
3.4.21.7 | KM(O2)YR-H | - |
Homo sapiens | |
3.4.21.7 | Kunitz-type inhibitor 2 | - |
Homo sapiens | |
3.4.21.7 | Leucaena-type trypsin inhibitor | - |
Homo sapiens | |
3.4.21.7 | nexin 2 | - |
Homo sapiens | |
3.4.21.7 | ONO-3307 | i.e. 4-sulfamoyl phenyl-4-guanidinobenzoate methanesulfonate | Homo sapiens | |
3.4.21.7 | plasminostreptin | - |
Homo sapiens | |
3.4.21.7 | TdPI tryptase inhibitor | - |
Homo sapiens | |
3.4.21.7 | textilinin-1 | - |
Homo sapiens | |
3.4.21.7 | tissue factor pathway inhibitor-1 | - |
Homo sapiens | |
3.4.21.7 | tissue factor pathway inhibitor-2 | - |
Homo sapiens | |
3.4.21.7 | Tranexamic acid | - |
Homo sapiens |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.4.21.7 | Fibrin + H2O | Homo sapiens | - |
? | - |
? | |
3.4.21.7 | MT1-matrix metalloproteinase + H2O | Homo sapiens | - |
? | - |
? | |
3.4.21.7 | pro-matrix metalloproteinase-1 + H2O | Homo sapiens | - |
matrix metalloproteinase-1 + ? | - |
? | |
3.4.21.7 | pro-matrix metalloproteinase-10 + H2O | Homo sapiens | - |
matrix metalloproteinase-10 + ? | - |
? | |
3.4.21.7 | pro-matrix metalloproteinase-13 + H2O | Homo sapiens | - |
matrix metalloproteinase-13 + ? | - |
? | |
3.4.21.7 | pro-matrix metalloproteinase-3 + H2O | Homo sapiens | - |
matrix metalloproteinase-3 + ? | - |
? | |
3.4.21.7 | pro-matrix metalloproteinase-9 + H2O | Homo sapiens | - |
matrix metalloproteinase-9 + ? | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.4.21.7 | Homo sapiens | P00747 | - |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.4.21.7 | Ac-KM(O2)YR + H2O | - |
Homo sapiens | ? | - |
? | |
3.4.21.7 | Ac-RM(O2)YR + H2O | - |
Homo sapiens | ? | - |
? | |
3.4.21.7 | Fibrin + H2O | - |
Homo sapiens | ? | - |
? | |
3.4.21.7 | MT1-matrix metalloproteinase + H2O | - |
Homo sapiens | ? | - |
? | |
3.4.21.7 | pro-matrix metalloproteinase-1 + H2O | - |
Homo sapiens | matrix metalloproteinase-1 + ? | - |
? | |
3.4.21.7 | pro-matrix metalloproteinase-10 + H2O | - |
Homo sapiens | matrix metalloproteinase-10 + ? | - |
? | |
3.4.21.7 | pro-matrix metalloproteinase-13 + H2O | - |
Homo sapiens | matrix metalloproteinase-13 + ? | - |
? | |
3.4.21.7 | pro-matrix metalloproteinase-3 + H2O | - |
Homo sapiens | matrix metalloproteinase-3 + ? | - |
? | |
3.4.21.7 | pro-matrix metalloproteinase-9 + H2O | - |
Homo sapiens | matrix metalloproteinase-9 + ? | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
3.4.21.7 | mu-plasminogen | - |
Homo sapiens |
EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|---|
3.4.21.7 | 0.000000087 | - |
DX-1000 | pH and temperature not specified in the publication | Homo sapiens | |
3.4.21.7 | 0.00000018 | - |
Aprotinin | pH and temperature not specified in the publication | Homo sapiens | |
3.4.21.7 | 0.00000032 | - |
Leucaena-type trypsin inhibitor | pH and temperature not specified in the publication | Homo sapiens | |
3.4.21.7 | 0.00000049 | - |
plasminostreptin | pH and temperature not specified in the publication | Homo sapiens | |
3.4.21.7 | 0.0000009 | - |
KD1-L17R | pH and temperature not specified in the publication | Homo sapiens | |
3.4.21.7 | 0.00000104 | - |
Kunitz-type inhibitor 2 | pH and temperature not specified in the publication | Homo sapiens | |
3.4.21.7 | 0.0000011 | - |
infestin | pH and temperature not specified in the publication | Homo sapiens | |
3.4.21.7 | 0.00000156 | - |
bdellin | pH and temperature not specified in the publication | Homo sapiens | |
3.4.21.7 | 0.0000022 | - |
CU-2010 | pH and temperature not specified in the publication | Homo sapiens | |
3.4.21.7 | 0.0000031 | - |
KM(O2)YR-H | pH and temperature not specified in the publication | Homo sapiens | |
3.4.21.7 | 0.0000035 | - |
textilinin-1 | pH and temperature not specified in the publication | Homo sapiens | |
3.4.21.7 | 0.0000038 | - |
Aedes aegypti trypsin inhibitor | pH and temperature not specified in the publication | Homo sapiens | |
3.4.21.7 | 0.00001 | - |
tissue factor pathway inhibitor-2 | pH and temperature not specified in the publication | Homo sapiens | |
3.4.21.7 | 0.000026 | - |
tissue factor pathway inhibitor-1 | pH and temperature not specified in the publication | Homo sapiens | |
3.4.21.7 | 0.000042 | - |
nexin 2 | pH and temperature not specified in the publication | Homo sapiens | |
3.4.21.7 | 0.000055 | - |
TdPI tryptase inhibitor | pH and temperature not specified in the publication | Homo sapiens | |
3.4.21.7 | 0.000081 | - |
amyloid precursor-like protein 2 | pH and temperature not specified in the publication | Homo sapiens | |
3.4.21.7 | 0.0001 | - |
bikunin | pH and temperature not specified in the publication | Homo sapiens | |
3.4.21.7 | 0.000127 | - |
chicken liver trypsin inhibitor | pH and temperature not specified in the publication | Homo sapiens | |
3.4.21.7 | 0.00033 | - |
ONO-3307 | pH and temperature not specified in the publication | Homo sapiens | |
3.4.21.7 | 0.00057 | - |
D-Ile-Phe-Lys-CH2Cl | pH and temperature not specified in the publication | Homo sapiens | |
3.4.21.7 | 0.002 | - |
bikazin salivary inhibitor | pH and temperature not specified in the publication | Homo sapiens |