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Literature summary extracted from

  • Weglarz-Tomczak, E.; Poreba, M.; Byzia, A.; Berlicki, L.; Nocek, B.; Mulligan, R.; Joachimiak, A.; Drag, M.; Mucha, A.
    An integrated approach to the ligand binding specificity of Neisseria meningitidis M1 alanine aminopeptidase by fluorogenic substrate profiling, inhibitory studies and molecular modeling (2013), Biochimie, 95, 419-428.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.4.11.2 expressed in Escherichia coli Neisseria meningitidis

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.11.2 (1-amino-3-phenylpropyl)phosphinic acid
-
 Neisseria meningitidis
3.4.11.2 (1-amino-3-phenylpropyl)phosphonic acid
-
 Neisseria meningitidis
3.4.11.2 (1-amino-4-carbamimidamidobutyl)phosphonic acid
-
 Neisseria meningitidis
3.4.11.2 3-[(1-amino-3-phenylpropyl)(hydroxy)phosphoryl]-2-(4-hydroxybenzyl)propanoic acid
-
 Neisseria meningitidis
3.4.11.2 3-[(1-amino-3-phenylpropyl)(hydroxy)phosphoryl]-2-benzylpropanoic acid
-
 Neisseria meningitidis
3.4.11.2 N-[[(1-amino-3-phenylpropyl)(hydroxy)phosphoryl]methy]tyrosine
-
 Neisseria meningitidis

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.4.11.2 0.027
-
 L-hArg-7-amido-4-carbamoylmethylcoumarin pH 7.5, 37°C Neisseria meningitidis
3.4.11.2 0.028
-
 L-Nva-7-amido-4-carbamoylmethylcoumarin pH 7.5, 37°C Neisseria meningitidis
3.4.11.2 0.03
-
 L-Abu(Bth)-7-amido-4-carbamoylmethylcoumarin pH 7.5, 37°C Neisseria meningitidis
3.4.11.2 0.041
-
 L-hCha-7-amido-4-carbamoylmethylcoumarin pH 7.5, 37°C Neisseria meningitidis
3.4.11.2 0.046
-
 L-Tyr-7-amido-4-carbamoylmethylcoumarin pH 7.5, 37°C Neisseria meningitidis
3.4.11.2 0.047
-
 L-hTyr-7-amido-4-carbamoylmethylcoumarin pH 7.5, 37°C Neisseria meningitidis
3.4.11.2 0.048
-
 L-Igl-7-amido-4-carbamoylmethylcoumarin pH 7.5, 37°C Neisseria meningitidis
3.4.11.2 0.05
-
 L-2-NaI-7-amido-4-carbamoylmethylcoumarin pH 7.5, 37°C Neisseria meningitidis
3.4.11.2 0.05
-
 L-Glu(Bzl)-7-amido-4-carbamoylmethylcoumarin pH 7.5, 37°C Neisseria meningitidis
3.4.11.2 0.052
-
 L-Nle-7-amido-4-carbamoylmethylcoumarin pH 7.5, 37°C Neisseria meningitidis
3.4.11.2 0.056
-
 L-hLeu-7-amido-4-carbamoylmethylcoumarin pH 7.5, 37°C Neisseria meningitidis
3.4.11.2 0.057
-
 3-OH-L-Pro-2-NaI-7-amido-4-carbamoylmethylcoumarin pH 7.5, 37°C Neisseria meningitidis
3.4.11.2 0.059
-
 L-allyl-Gly-7-amido-4-carbamoylmethylcoumarin pH 7.5, 37°C Neisseria meningitidis
3.4.11.2 0.059
-
 6-Obzl-L-Nle-7-amido-4-carbamoylmethylcoumarin pH 7.5, 37°C Neisseria meningitidis
3.4.11.2 0.06
-
 L-Arg(NO2)-7-amido-4-carbamoylmethylcoumarin pH 7.5, 37°C Neisseria meningitidis
3.4.11.2 0.061
-
 L-neopentyl-Gly-7-amido-4-carbamoylmethylcoumarin pH 7.5, 37°C Neisseria meningitidis
3.4.11.2 0.064
-
 L-Arg-7-amido-4-carbamoylmethylcoumarin pH 7.5, 37°C Neisseria meningitidis
3.4.11.2 0.079
-
 L-hSer-7-amido-4-carbamoylmethylcoumarin pH 7.5, 37°C Neisseria meningitidis
3.4.11.2 0.08
-
 L-Met-7-amido-4-carbamoylmethylcoumarin pH 7.5, 37°C Neisseria meningitidis
3.4.11.2 0.085
-
 L-Leu-7-amido-4-carbamoylmethylcoumarin pH 7.5, 37°C Neisseria meningitidis
3.4.11.2 0.088
-
 L-Lys-7-amido-4-carbamoylmethylcoumarin pH 7.5, 37°C Neisseria meningitidis
3.4.11.2 0.1
-
 L-hPhe-7-amido-4-carbamoylmethylcoumarin pH 7.5, 37°C Neisseria meningitidis
3.4.11.2 0.117
-
 L-Asp(Bzl)-7-amido-4-carbamoylmethylcoumarin pH 7.5, 37°C Neisseria meningitidis
3.4.11.2 0.121
-
 L-propargyl-Gly-7-amido-4-carbamoylmethylcoumarin pH 7.5, 37°C Neisseria meningitidis
3.4.11.2 0.121
-
 L-Cha-7-amido-4-carbamoylmethylcoumarin pH 7.5, 37°C Neisseria meningitidis
3.4.11.2 0.146
-
 L-hSer(Bzl)-7-amido-4-carbamoylmethylcoumarin pH 7.5, 37°C Neisseria meningitidis
3.4.11.2 0.149
-
 4-Cl-L-Phe-7-amido-4-carbamoylmethylcoumarin pH 7.5, 37°C Neisseria meningitidis
3.4.11.2 0.161
-
 L-2-amino-3-(2-benzothiazolyl)butyric acid-7-amido-4-carbamoylmethylcoumarin pH 7.5, 37°C Neisseria meningitidis
3.4.11.2 0.174
-
 L-Ala-7-amido-4-carbamoylmethylcoumarin pH 7.5, 37°C Neisseria meningitidis
3.4.11.2 0.25
-
 L-Phe-7-amido-4-carbamoylmethylcoumarin pH 7.5, 37°C, value above Neisseria meningitidis
3.4.11.2 0.25
-
 4-Br-L-Phe-7-amido-4-carbamoylmethylcoumarin pH 7.5, 37°C, value above Neisseria meningitidis
3.4.11.2 0.25
-
 L-Gln-7-amido-4-carbamoylmethylcoumarin pH 7.5, 37°C, value above Neisseria meningitidis
3.4.11.2 0.25
-
 Gly-7-amido-4-carbamoylmethylcoumarin pH 7.5, 37°C, value higher than Neisseria meningitidis

Organism

EC Number Organism UniProt Comment Textmining
3.4.11.2 Neisseria meningitidis
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.11.2 3-OH-L-Pro-2-NaI-7-amido-4-carbamoylmethylcoumarin + H2O
-
 Neisseria meningitidis 3-OH-L-Pro + 7-amino-4-carbamoylmethylcoumarin
-
 ?
3.4.11.2 4-Br-L-Phe-7-amido-4-carbamoylmethylcoumarin + H2O
-
 Neisseria meningitidis 4-Br-L-Phe + 7-amino-4-carbamoylmethylcoumarin
-
 ?
3.4.11.2 4-Cl-L-Phe-7-amido-4-carbamoylmethylcoumarin + H2O
-
 Neisseria meningitidis 4-Cl-L-Phe + 7-amino-4-carbamoylmethylcoumarin
-
 ?
3.4.11.2 6-O-Bzl-L-Nle-7-amido-4-carbamoylmethylcoumarin + H2O
-
 Neisseria meningitidis 6-O-Bzl-L-Nle + 7-amino-4-carbamoylmethylcoumarin
-
 ?
3.4.11.2 Gly-7-amido-4-carbamoylmethylcoumarin + H2O
-
 Neisseria meningitidis Gly + 7-amino-4-carbamoylmethylcoumarin
-
 ?
3.4.11.2 L-2-amino-3-(2-benzothiazolyl)butyric acid-7-amido-4-carbamoylmethylcoumarin + H2O
-
 Neisseria meningitidis L-2-amino-3-(2-benzothiazolyl)butyric acid + 7-amino-4-carbamoylmethylcoumarin
-
 ?
3.4.11.2 L-2-NaI-7-amido-4-carbamoylmethylcoumarin + H2O
-
 Neisseria meningitidis L-2-NaI + 7-amino-4-carbamoylmethylcoumarin
-
 ?
3.4.11.2 L-Abu(Bth)-7-amido-4-carbamoylmethylcoumarin + H2O
-
 Neisseria meningitidis L-Abu(Bth) + 7-amino-4-carbamoylmethylcoumarin
-
 ?
3.4.11.2 L-Ala-7-amido-4-carbamoylmethylcoumarin + H2O
-
 Neisseria meningitidis L-Ala + 7-amino-4-carbamoylmethylcoumarin
-
 ?
3.4.11.2 L-allyl-Gly-7-amido-4-carbamoylmethylcoumarin + H2O
-
 Neisseria meningitidis L-allyl-Gly + 7-amino-4-carbamoylmethylcoumarin
-
 ?
3.4.11.2 L-Arg(NO2)-7-amido-4-carbamoylmethylcoumarin + H2O
-
 Neisseria meningitidis L-Arg(NO2) + 7-amino-4-carbamoylmethylcoumarin
-
 ?
3.4.11.2 L-Arg-7-amido-4-carbamoylmethylcoumarin + H2O
-
 Neisseria meningitidis L-Arg + 7-amino-4-carbamoylmethylcoumarin
-
 ?
3.4.11.2 L-Asp(Bzl)-7-amido-4-carbamoylmethylcoumarin + H2O
-
 Neisseria meningitidis L-Asp(Bzl) + 7-amino-4-carbamoylmethylcoumarin
-
 ?
3.4.11.2 L-Cha-7-amido-4-carbamoylmethylcoumarin + H2O
-
 Neisseria meningitidis L-Cha + 7-amino-4-carbamoylmethylcoumarin
-
 ?
3.4.11.2 L-Gln-7-amido-4-carbamoylmethylcoumarin + H2O
-
 Neisseria meningitidis L-Gln + 7-amino-4-carbamoylmethylcoumarin
-
 ?
3.4.11.2 L-Glu(Bzl)-7-amido-4-carbamoylmethylcoumarin + H2O
-
 Neisseria meningitidis L-Glu(Bzl) + 7-amino-4-carbamoylmethylcoumarin
-
 ?
3.4.11.2 L-hArg-7-amido-4-carbamoylmethylcoumarin + H2O
-
 Neisseria meningitidis L-hArg + 7-amino-4-carbamoylmethylcoumarin
-
 ?
3.4.11.2 L-hCha-7-amido-4-carbamoylmethylcoumarin + H2O
-
 Neisseria meningitidis L-hCha + 7-amino-4-carbamoylmethylcoumarin
-
 ?
3.4.11.2 L-hLeu-7-amido-4-carbamoylmethylcoumarin + H2O
-
 Neisseria meningitidis L-hLeu + 7-amino-4-carbamoylmethylcoumarin
-
 ?
3.4.11.2 L-hPhe-7-amido-4-carbamoylmethylcoumarin + H2O
-
 Neisseria meningitidis L-hPhe + 7-amino-4-carbamoylmethylcoumarin
-
 ?
3.4.11.2 L-hSer(Bzl)-7-amido-4-carbamoylmethylcoumarin + H2O
-
 Neisseria meningitidis L-hSer(Bzl) + 7-amino-4-carbamoylmethylcoumarin
-
 ?
3.4.11.2 L-hSer-7-amido-4-carbamoylmethylcoumarin + H2O
-
 Neisseria meningitidis L-hSer + 7-amino-4-carbamoylmethylcoumarin
-
 ?
3.4.11.2 L-hTyr-7-amido-4-carbamoylmethylcoumarin + H2O
-
 Neisseria meningitidis L-hTyr + 7-amino-4-carbamoylmethylcoumarin
-
 ?
3.4.11.2 L-Igl-7-amido-4-carbamoylmethylcoumarin + H2O
-
 Neisseria meningitidis L-Igl + 7-amino-4-carbamoylmethylcoumarin
-
 ?
3.4.11.2 L-Leu-7-amido-4-carbamoylmethylcoumarin + H2O
-
 Neisseria meningitidis L-Leu + 7-amino-4-carbamoylmethylcoumarin
-
 ?
3.4.11.2 L-Lys-7-amido-4-carbamoylmethylcoumarin + H2O
-
 Neisseria meningitidis L-Lys + 7-amino-4-carbamoylmethylcoumarin
-
 ?
3.4.11.2 L-Met-7-amido-4-carbamoylmethylcoumarin + H2O
-
 Neisseria meningitidis L-Met + 7-amino-4-carbamoylmethylcoumarin
-
 ?
3.4.11.2 L-neopentyl-Gly-7-amido-4-carbamoylmethylcoumarin + H2O
-
 Neisseria meningitidis L-neopentyl-Gly + 7-amino-4-carbamoylmethylcoumarin
-
 ?
3.4.11.2 L-Nle-7-amido-4-carbamoylmethylcoumarin + H2O
-
 Neisseria meningitidis L-Nle + 7-amino-4-carbamoylmethylcoumarin
-
 ?
3.4.11.2 L-Nva-7-amido-4-carbamoylmethylcoumarin + H2O
-
 Neisseria meningitidis L-Nva + 7-amino-4-carbamoylmethylcoumarin
-
 ?
3.4.11.2 L-Phe-7-amido-4-carbamoylmethylcoumarin + H2O
-
 Neisseria meningitidis L-Phe + 7-amino-4-carbamoylmethylcoumarin
-
 ?
3.4.11.2 L-propargyl-Gly-7-amido-4-carbamoylmethylcoumarin + H2O
-
 Neisseria meningitidis L-propargyl-Gly + 7-amino-4-carbamoylmethylcoumarin
-
 ?
3.4.11.2 L-Tyr-7-amido-4-carbamoylmethylcoumarin + H2O
-
 Neisseria meningitidis L-Tyr + 7-amino-4-carbamoylmethylcoumarin
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.4.11.2 NmAPN
-
 Neisseria meningitidis

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
3.4.11.2 37
-
 assay at Neisseria meningitidis

Turnover Number [1/s]

EC Number Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
3.4.11.2 1.19
-
 3-OH-L-Pro-2-NaI-7-amido-4-carbamoylmethylcoumarin pH 7.5, 37°C Neisseria meningitidis
3.4.11.2 1.64
-
 L-neopentyl-Gly-7-amido-4-carbamoylmethylcoumarin pH 7.5, 37°C Neisseria meningitidis
3.4.11.2 1.66
-
 L-Tyr-7-amido-4-carbamoylmethylcoumarin pH 7.5, 37°C Neisseria meningitidis
3.4.11.2 1.72
-
 L-Igl-7-amido-4-carbamoylmethylcoumarin pH 7.5, 37°C Neisseria meningitidis
3.4.11.2 2.6
-
 L-2-NaI-7-amido-4-carbamoylmethylcoumarin pH 7.5, 37°C Neisseria meningitidis
3.4.11.2 2.65
-
 L-hLeu-7-amido-4-carbamoylmethylcoumarin pH 7.5, 37°C Neisseria meningitidis
3.4.11.2 2.72
-
 L-Nle-7-amido-4-carbamoylmethylcoumarin pH 7.5, 37°C Neisseria meningitidis
3.4.11.2 3.19
-
 L-hCha-7-amido-4-carbamoylmethylcoumarin pH 7.5, 37°C Neisseria meningitidis
3.4.11.2 3.24
-
 6-Obzl-L-Nle-7-amido-4-carbamoylmethylcoumarin pH 7.5, 37°C Neisseria meningitidis
3.4.11.2 3.33
-
 L-Nva-7-amido-4-carbamoylmethylcoumarin pH 7.5, 37°C Neisseria meningitidis
3.4.11.2 3.45
-
 L-Leu-7-amido-4-carbamoylmethylcoumarin pH 7.5, 37°C Neisseria meningitidis
3.4.11.2 3.64
-
 L-Asp(Bzl)-7-amido-4-carbamoylmethylcoumarin pH 7.5, 37°C Neisseria meningitidis
3.4.11.2 3.84
-
 L-Cha-7-amido-4-carbamoylmethylcoumarin pH 7.5, 37°C Neisseria meningitidis
3.4.11.2 4.16
-
 L-hSer(Bzl)-7-amido-4-carbamoylmethylcoumarin pH 7.5, 37°C Neisseria meningitidis
3.4.11.2 4.9
-
 L-allyl-Gly-7-amido-4-carbamoylmethylcoumarin pH 7.5, 37°C Neisseria meningitidis
3.4.11.2 5.05
-
 4-Cl-L-Phe-7-amido-4-carbamoylmethylcoumarin pH 7.5, 37°C Neisseria meningitidis
3.4.11.2 5.25
-
 L-Abu(Bth)-7-amido-4-carbamoylmethylcoumarin pH 7.5, 37°C Neisseria meningitidis
3.4.11.2 5.6
-
 L-Glu(Bzl)-7-amido-4-carbamoylmethylcoumarin pH 7.5, 37°C Neisseria meningitidis
3.4.11.2 5.99
-
 L-Met-7-amido-4-carbamoylmethylcoumarin pH 7.5, 37°C Neisseria meningitidis
3.4.11.2 6.15
-
 L-Lys-7-amido-4-carbamoylmethylcoumarin pH 7.5, 37°C Neisseria meningitidis
3.4.11.2 6.23
-
 L-hSer-7-amido-4-carbamoylmethylcoumarin pH 7.5, 37°C Neisseria meningitidis
3.4.11.2 7.25
-
 L-Arg(NO2)-7-amido-4-carbamoylmethylcoumarin pH 7.5, 37°C Neisseria meningitidis
3.4.11.2 7.74
-
 L-propargyl-Gly-7-amido-4-carbamoylmethylcoumarin pH 7.5, 37°C Neisseria meningitidis
3.4.11.2 8.63
-
 L-hArg-7-amido-4-carbamoylmethylcoumarin pH 7.5, 37°C Neisseria meningitidis
3.4.11.2 12.7
-
 L-hTyr-7-amido-4-carbamoylmethylcoumarin pH 7.5, 37°C Neisseria meningitidis
3.4.11.2 13
-
 L-hPhe-7-amido-4-carbamoylmethylcoumarin pH 7.5, 37°C Neisseria meningitidis
3.4.11.2 13.1
-
 L-Arg-7-amido-4-carbamoylmethylcoumarin pH 7.5, 37°C Neisseria meningitidis
3.4.11.2 13.8
-
 L-2-amino-3-(2-benzothiazolyl)butyric acid-7-amido-4-carbamoylmethylcoumarin pH 7.5, 37°C Neisseria meningitidis
3.4.11.2 28.4
-
 L-Ala-7-amido-4-carbamoylmethylcoumarin pH 7.5, 37°C Neisseria meningitidis

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.4.11.2 7.5
-
 assay at Neisseria meningitidis

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
3.4.11.2 0.000054
-
 3-[(1-amino-3-phenylpropyl)(hydroxy)phosphoryl]-2-(4-hydroxybenzyl)propanoic acid pH 7.5, 37°C Neisseria meningitidis
3.4.11.2 0.000302
-
 3-[(1-amino-3-phenylpropyl)(hydroxy)phosphoryl]-2-benzylpropanoic acid pH 7.5, 37°C Neisseria meningitidis
3.4.11.2 0.00126
-
 (1-amino-3-phenylpropyl)phosphonic acid pH 7.5, 37°C Neisseria meningitidis
3.4.11.2 0.00145
-
 (1-amino-3-phenylpropyl)phosphinic acid pH 7.5, 37°C Neisseria meningitidis
3.4.11.2 0.00146
-
 (1-amino-4-carbamimidamidobutyl)phosphonic acid pH 7.5, 37°C Neisseria meningitidis
3.4.11.2 0.00251
-
 N-[[(1-amino-3-phenylpropyl)(hydroxy)phosphoryl]methy]tyrosine pH 7.5, 37°C Neisseria meningitidis

IC50 Value

EC Number IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
3.4.11.2 0.00007
-
 pH 7.5, 37°C Neisseria meningitidis 3-[(1-amino-3-phenylpropyl)(hydroxy)phosphoryl]-2-(4-hydroxybenzyl)propanoic acid
3.4.11.2 0.000397
-
 pH 7.5, 37°C Neisseria meningitidis 3-[(1-amino-3-phenylpropyl)(hydroxy)phosphoryl]-2-benzylpropanoic acid
3.4.11.2 0.00166
-
 pH 7.5, 37°C Neisseria meningitidis (1-amino-3-phenylpropyl)phosphonic acid
3.4.11.2 0.00191
-
 pH 7.5, 37°C Neisseria meningitidis (1-amino-3-phenylpropyl)phosphinic acid
3.4.11.2 0.00191
-
 pH 7.5, 37°C Neisseria meningitidis (1-amino-4-carbamimidamidobutyl)phosphonic acid
3.4.11.2 0.00329
-
 pH 7.5, 37°C Neisseria meningitidis N-[[(1-amino-3-phenylpropyl)(hydroxy)phosphoryl]methy]tyrosine

kcat/KM [mM/s]

EC Number kcat/KM Value [1/mMs-1] kcat/KM Value Maximum [1/mMs-1] Substrate Comment Organism Structure
3.4.11.2 21
-
 3-OH-L-Pro-2-NaI-7-amido-4-carbamoylmethylcoumarin pH 7.5, 37°C Neisseria meningitidis
3.4.11.2 27
-
 L-neopentyl-Gly-7-amido-4-carbamoylmethylcoumarin pH 7.5, 37°C Neisseria meningitidis
3.4.11.2 28
-
 L-hSer(Bzl)-7-amido-4-carbamoylmethylcoumarin pH 7.5, 37°C Neisseria meningitidis
3.4.11.2 31
-
 L-Cha-7-amido-4-carbamoylmethylcoumarin pH 7.5, 37°C Neisseria meningitidis
3.4.11.2 31
-
 L-Asp(Bzl)-7-amido-4-carbamoylmethylcoumarin pH 7.5, 37°C Neisseria meningitidis
3.4.11.2 34
-
 4-Cl-L-Phe-7-amido-4-carbamoylmethylcoumarin pH 7.5, 37°C Neisseria meningitidis
3.4.11.2 35
-
 L-Igl-7-amido-4-carbamoylmethylcoumarin pH 7.5, 37°C Neisseria meningitidis
3.4.11.2 36
-
 L-Tyr-7-amido-4-carbamoylmethylcoumarin pH 7.5, 37°C Neisseria meningitidis
3.4.11.2 40
-
 L-Leu-7-amido-4-carbamoylmethylcoumarin pH 7.5, 37°C Neisseria meningitidis
3.4.11.2 46
-
 L-hLeu-7-amido-4-carbamoylmethylcoumarin pH 7.5, 37°C Neisseria meningitidis
3.4.11.2 51
-
 L-2-NaI-7-amido-4-carbamoylmethylcoumarin pH 7.5, 37°C Neisseria meningitidis
3.4.11.2 52
-
 L-Nle-7-amido-4-carbamoylmethylcoumarin pH 7.5, 37°C Neisseria meningitidis
3.4.11.2 54
-
 6-Obzl-L-Nle-7-amido-4-carbamoylmethylcoumarin pH 7.5, 37°C Neisseria meningitidis
3.4.11.2 63
-
 L-propargyl-Gly-7-amido-4-carbamoylmethylcoumarin pH 7.5, 37°C Neisseria meningitidis
3.4.11.2 69
-
 L-Lys-7-amido-4-carbamoylmethylcoumarin pH 7.5, 37°C Neisseria meningitidis
3.4.11.2 74
-
 L-Met-7-amido-4-carbamoylmethylcoumarin pH 7.5, 37°C Neisseria meningitidis
3.4.11.2 77
-
 L-hCha-7-amido-4-carbamoylmethylcoumarin pH 7.5, 37°C Neisseria meningitidis
3.4.11.2 79
-
 L-hSer-7-amido-4-carbamoylmethylcoumarin pH 7.5, 37°C Neisseria meningitidis
3.4.11.2 82
-
 L-allyl-Gly-7-amido-4-carbamoylmethylcoumarin pH 7.5, 37°C Neisseria meningitidis
3.4.11.2 85
-
 L-2-amino-3-(2-benzothiazolyl)butyric acid-7-amido-4-carbamoylmethylcoumarin pH 7.5, 37°C Neisseria meningitidis
3.4.11.2 111
-
 L-Glu(Bzl)-7-amido-4-carbamoylmethylcoumarin pH 7.5, 37°C Neisseria meningitidis
3.4.11.2 116
-
 L-Nva-7-amido-4-carbamoylmethylcoumarin pH 7.5, 37°C Neisseria meningitidis
3.4.11.2 120
-
 L-Arg(NO2)-7-amido-4-carbamoylmethylcoumarin pH 7.5, 37°C Neisseria meningitidis
3.4.11.2 129
-
 L-hPhe-7-amido-4-carbamoylmethylcoumarin pH 7.5, 37°C Neisseria meningitidis
3.4.11.2 163
-
 L-Ala-7-amido-4-carbamoylmethylcoumarin pH 7.5, 37°C Neisseria meningitidis
3.4.11.2 173
-
 L-Abu(Bth)-7-amido-4-carbamoylmethylcoumarin pH 7.5, 37°C Neisseria meningitidis
3.4.11.2 205
-
 L-Arg-7-amido-4-carbamoylmethylcoumarin pH 7.5, 37°C Neisseria meningitidis
3.4.11.2 270
-
 L-hTyr-7-amido-4-carbamoylmethylcoumarin pH 7.5, 37°C Neisseria meningitidis
3.4.11.2 312
-
 L-hArg-7-amido-4-carbamoylmethylcoumarin pH 7.5, 37°C Neisseria meningitidis