EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
4.2.1.127 | beta-myrcene + H2O | Castellaniella defragrans | - |
(3S)-linalool | - |
? | |
4.2.1.127 | beta-myrcene + H2O | Castellaniella defragrans 65Phen | - |
(3S)-linalool | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
4.2.1.127 | Castellaniella defragrans | E1XUJ2 | i.e. Alcaligenes defragrans, gene ldi | - |
4.2.1.127 | Castellaniella defragrans 65Phen | E1XUJ2 | i.e. Alcaligenes defragrans, gene ldi | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
4.2.1.127 | beta-myrcene + H2O | - |
Castellaniella defragrans | (3S)-linalool | - |
? | |
4.2.1.127 | beta-myrcene + H2O | stereospecific reaction, introduction of the hydroxy group on the si-face of beta-myrcene | Castellaniella defragrans | (3S)-linalool | (3S)-linalool is formed with an enantiomeric excess of at least 95.4%, (3R)-inalool is not detected | ? | |
4.2.1.127 | beta-myrcene + H2O | - |
Castellaniella defragrans 65Phen | (3S)-linalool | - |
? | |
4.2.1.127 | beta-myrcene + H2O | stereospecific reaction, introduction of the hydroxy group on the si-face of beta-myrcene | Castellaniella defragrans 65Phen | (3S)-linalool | (3S)-linalool is formed with an enantiomeric excess of at least 95.4%, (3R)-inalool is not detected | ? | |
4.2.1.127 | additional information | the thermodynamically favoured direction is the isomerization of geraniol to linalool and the dehydration reaction to beta-myrcene | Castellaniella defragrans | ? | - |
? | |
4.2.1.127 | additional information | the thermodynamically favoured direction is the isomerization of geraniol to linalool and the dehydration reaction to beta-myrcene | Castellaniella defragrans 65Phen | ? | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
4.2.1.127 | LDI | - |
Castellaniella defragrans |
4.2.1.127 | ldi/LDI | - |
Castellaniella defragrans |
4.2.1.127 | linalool dehydratase-isomerase | - |
Castellaniella defragrans |
EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|---|
4.2.1.127 | 37 | - |
assay at | Castellaniella defragrans |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
4.2.1.127 | 9 | - |
assay at | Castellaniella defragrans |
EC Number | General Information | Comment | Organism |
---|---|---|---|
4.2.1.127 | metabolism | the bifunctional linalool dehydratase-isomerase ldi/LDI is the initial enzyme in the anaerobic beta-myrcene degradation pathway and catalyzes the hydration of beta-myrcene to (S)-(+)-linalool and its isomerization to geraniol. A high-affinity geraniol dehydrogenase geoA/GeDH and a geranial dehydrogenase geoB/GaDH contribute to the formation of geranic acid | Castellaniella defragrans |