Literature summary extracted from

Nogueira, S.V.; Backstedt, B.T.; Smith, A.A.; Qin, J.H.; Wunder, E.A.; Ko, A.; Pal, U.
Leptospira interrogans enolase is secreted extracellularly and interacts with plasminogen (2013), PLoS ONE, 8, e78150.

Localization

EC Number	Localization	Comment	Organism	GeneOntology No.	Textmining
4.2.1.11	extracellular	-	Leptospira interrogans	-	-

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
4.2.1.11	2-phospho-D-glycerate	Leptospira interrogans	-	phosphoenolpyruvate + H2O	-	?
4.2.1.11	2-phospho-D-glycerate	Leptospira interrogans 56601	-	phosphoenolpyruvate + H2O	-	?

Organism

EC Number	Organism	UniProt	Comment	Textmining
4.2.1.11	Leptospira interrogans	-	serovar Lai	-
4.2.1.11	Leptospira interrogans 56601	-	serovar Lai	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
4.2.1.11	2-phospho-D-glycerate	-	Leptospira interrogans	phosphoenolpyruvate + H2O	-	?
4.2.1.11	2-phospho-D-glycerate	-	Leptospira interrogans 56601	phosphoenolpyruvate + H2O	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
4.2.1.11	enolase	-	Leptospira interrogans

General Information

EC Number	General Information	Comment	Organism
4.2.1.11	physiological function	the enzyme plays a role in pathogen interaction with host molecules like plasminogen, which may contribute to the pathogenesis of leptospirosis	Leptospira interrogans

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Release 2023.1 (January 2023)