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Literature summary extracted from

  • Sun, Y.; Zhang, R.; Li, D.; Feng, L.; Wu, D.; Feng, L.; Huang, P.; Ren, Y.; Feng, J.; Xiao, S.; Wan, J.
    Pharmacophore-based virtual screening and experimental validation of novel inhibitors against cyanobacterial fructose-1,6-/sedoheptulose-1,7-bisphosphatase (2014), J. Chem. Inf. Model., 54, 894-901.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.1.3.37 expressed in Escherichia coli BL21(DE3) cells Synechocystis sp.

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.3.37 2-[2-(4-amino-1,2,5-oxadiazol-3-yl)-1H-indol-1-yl]-N'-[(E)-(4-methylphenyl)methylidene]acetohydrazide
-
 Synechocystis sp.
3.1.3.37 2-[2-(4-amino-1,2,5-oxadiazol-3-yl)-1H-indol-1-yl]-N'-[(E)-(5-hydroxy-2-methylphenyl)methylidene]acetohydrazide
-
 Synechocystis sp.
3.1.3.37 2-[2-(4-amino-1,2,5-oxadiazol-3-yl)-1H-indol-1-yl]-N-(2,3-dihydro-1H-inden-5-yl)acetamide
-
 Synechocystis sp.
3.1.3.37 2-[2-(4-amino-1,2,5-oxadiazol-3-yl)-1H-indol-1-yl]-N-(2,6-dimethylphenyl)acetamide
-
 Synechocystis sp.
3.1.3.37 2-[2-(4-amino-1,2,5-oxadiazol-3-yl)-1H-indol-1-yl]-N-(3-fluoro-4-methylphenyl)acetamide
-
 Synechocystis sp.
3.1.3.37 2-[2-(4-amino-1,2,5-oxadiazol-3-yl)-1H-indol-1-yl]-N-(3-oxo-1,3-dihydro-2-benzofuran-5-yl)acetamide
-
 Synechocystis sp.
3.1.3.37 4-[1-(4-chlorobenzyl)-1H-indol-2-yl]-1,2,5-oxadiazol-3-amine
-
 Synechocystis sp.
3.1.3.37 methyl 4-([[2-(4-amino-1,2,5-oxadiazol-3-yl)-1H-indol-1-yl]acetyl]amino)benzoate
-
 Synechocystis sp.

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.3.37 sedoheptulose 1,7-bisphosphate + H2O Synechocystis sp.
-
 sedoheptulose 7-phosphate + phosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.1.3.37 Synechocystis sp. P73922
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.1.3.37
-
 Synechocystis sp.

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.3.37 sedoheptulose 1,7-bisphosphate + H2O
-
 Synechocystis sp. sedoheptulose 7-phosphate + phosphate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.1.3.37 FBP/SBPase
-
 Synechocystis sp.
3.1.3.37 fructose-1,6-/sedoheptulose-1,7-bisphosphatase
-
 Synechocystis sp.