Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Tekoah, Y.; Tzaban, S.; Kizhner, T.; Hainrichson, M.; Gantman, A.; Golembo, M.; Aviezer, D.; Shaaltiel, Y.
    Glycosylation and functionality of recombinant beta-glucocerebrosidase from various production systems (2013), Biosci. Rep., 33, e00071.
    View publication on PubMedView publication on EuropePMC

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.2.1.45 0.233
-
 glucosylceramide taliglucerase alfa, at pH 5.5 and 37°C Homo sapiens
3.2.1.45 0.234
-
 glucosylceramide imiglucerase, at pH 5.5 and 37°C Homo sapiens
3.2.1.45 0.247
-
 glucosylceramide velaglucerase alfa, at pH 5.5 and 37°C Homo sapiens
3.2.1.45 1.06
-
 4-methylumbelliferyl beta-D-glucopyranoside taliglucerase alfa, at pH 5.5 and 37°C Homo sapiens
3.2.1.45 1.107
-
 4-methylumbelliferyl beta-D-glucopyranoside velaglucerase alfa, at pH 5.5 and 37°C Homo sapiens
3.2.1.45 1.127
-
 4-methylumbelliferyl beta-D-glucopyranoside imiglucerase, at pH 5.5 and 37°C Homo sapiens
3.2.1.45 2.331
-
 4-nitrophenyl beta-D-glucopyranoside velaglucerase alfa, at pH 5.5 and 37°C Homo sapiens
3.2.1.45 2.415
-
 4-nitrophenyl beta-D-glucopyranoside imiglucerase, at pH 5.5 and 37°C Homo sapiens
3.2.1.45 2.592
-
 4-nitrophenyl beta-D-glucopyranoside taliglucerase alfa, at pH 5.5 and 37°C Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.2.1.45 glucocerebroside + H2O Homo sapiens
-
 ceramide + D-glucose
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.2.1.45 Homo sapiens
-
-
-

Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
3.2.1.45 glycoprotein
-
 Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.2.1.45 4-methylumbelliferyl beta-D-glucopyranoside + H2O
-
 Homo sapiens 4-methylumbelliferone + beta-D-glucopyranose
-
 ?
3.2.1.45 4-nitrophenyl beta-D-glucopyranoside + H2O
-
 Homo sapiens 4-nitrophenol + D-glucopyranose
-
 ?
3.2.1.45 glucocerebroside + H2O
-
 Homo sapiens ceramide + D-glucose
-
 ?
3.2.1.45 glucosylceramide + H2O
-
 Homo sapiens beta-D-glucose + ceramide
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.2.1.45 beta-glucocerebrosidase
-
 Homo sapiens
3.2.1.45 Imiglucerase
-
 Homo sapiens
3.2.1.45 taliglucerase alfa
-
 Homo sapiens
3.2.1.45 velaglucerase alfa
-
 Homo sapiens