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Literature summary extracted from

  • Lee, S.K.; Park, J.W.; Kim, J.W.; Jung, W.S.; Park, S.R.; Choi, C.Y.; Kim, E.S.; Kim, B.S.; Ahn, J.S.; Sherman, D.H.; Yoon, Y.J.
    Neopikromycin and novapikromycin from the pikromycin biosynthetic pathway of Streptomyces venezuelae (2006), J. Nat. Prod., 69, 847-849.
    View publication on PubMed

Organism

EC Number Organism UniProt Comment Textmining
1.14.15.33 Streptomyces venezuelae O87605
-
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.15.33 10-deoxymethymycin + 2 reduced ferredoxin [iron-sulfur] cluster + 2 H+ + O2 i.e. YC-17 Streptomyces venezuelae methymycin + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O
-
 ?
1.14.15.33 10-deoxymethymycin + 2 reduced ferredoxin [iron-sulfur] cluster + 2 H+ + O2
-
 Streptomyces venezuelae neomethymycin + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O
-
 ?
1.14.15.33 narbomycin + 2 reduced ferredoxin [iron-sulfur] cluster + 2 H+ + O2
-
 Streptomyces venezuelae neopikromycin + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O C14 hydroxylation product of narbomycin ?
1.14.15.33 narbomycin + 2 reduced ferredoxin [iron-sulfur] cluster + 2 H+ + O2
-
 Streptomyces venezuelae pikromycin + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O
-
 ?
1.14.15.33 narbomycin + 2 reduced ferredoxin [iron-sulfur] cluster + 2 H+ + O2
-
 Streptomyces venezuelae novapikromycin + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O C12,C14-dihydroxylated product of narbomycin ?