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Literature summary extracted from

  • Horvath, S.E.; Boettinger, L.; Voegtle, F.N.; Wiedemann, N.; Meisinger, C.; Becker, T.; Daum, G.
    Processing and topology of the yeast mitochondrial phosphatidylserine decarboxylase 1 (2012), J. Biol. Chem., 287, 36744-36755.
    View publication on PubMedView publication on EuropePMC

Protein Variants

EC Number Protein Variants Comment Organism
4.1.1.65 S463A the mutant does not display detectable decarboxylase activity due to the inability to generate the active site of the enzyme Saccharomyces cerevisiae

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
4.1.1.65 mitochondrion the enzyme requires integration into the inner mitochondrial membrane for full enzymatic activity Saccharomyces cerevisiae 5739
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
4.1.1.65 10000
-
 1 * 45000 + 1 * 10000, SDS-PAGE Saccharomyces cerevisiae
4.1.1.65 45000
-
 1 * 45000 + 1 * 10000, SDS-PAGE Saccharomyces cerevisiae
4.1.1.65 55000
-
 gel filtration Saccharomyces cerevisiae

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.1.1.65 Phosphatidyl-L-serine Saccharomyces cerevisiae
-
 Phosphatidylethanolamine + CO2
-
 ?
4.1.1.65 Phosphatidyl-L-serine Saccharomyces cerevisiae BY4741
-
 Phosphatidylethanolamine + CO2
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
4.1.1.65 Saccharomyces cerevisiae
-
-
-
4.1.1.65 Saccharomyces cerevisiae BY4741
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.1.1.65 Phosphatidyl-L-serine
-
 Saccharomyces cerevisiae Phosphatidylethanolamine + CO2
-
 ?
4.1.1.65 Phosphatidyl-L-serine
-
 Saccharomyces cerevisiae BY4741 Phosphatidylethanolamine + CO2
-
 ?

Subunits

EC Number Subunits Comment Organism
4.1.1.65 heterodimer 1 * 45000 + 1 * 10000, SDS-PAGE Saccharomyces cerevisiae

Synonyms

EC Number Synonyms Comment Organism
4.1.1.65 phosphatidylserine decarboxylase 1
-
 Saccharomyces cerevisiae
4.1.1.65 PSD1
-
 Saccharomyces cerevisiae