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Literature summary extracted from

  • Kwon, O.; Kotsakis, A.; Meganathan, R.
    Ubiquinone (coenzyme Q) biosynthesis in Escherichia coli: identification of the ubiF gene (2000), FEMS Microbiol. Lett., 186, 157-161.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.14.99.60
-
 Escherichia coli

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.14.99.60 42953
-
 x * 42953, calculated from sequence Escherichia coli

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.14.99.60 6-methoxy-3-methyl-2-all-trans-octaprenyl-1,4-benzoquinol + a reduced electron acceptor + oxygen Escherichia coli the enzyme catalyzes a reaction in the ubiquinone biosynthesis pathway an oxidized electron acceptor + 3-demethylubiquinol-8 + H2O
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.14.99.60 Escherichia coli P75728
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.99.60 6-methoxy-3-methyl-2-all-trans-octaprenyl-1,4-benzoquinol + a reduced electron acceptor + oxygen the enzyme catalyzes a reaction in the ubiquinone biosynthesis pathway Escherichia coli an oxidized electron acceptor + 3-demethylubiquinol-8 + H2O
-
 ?
1.14.99.60 6-methoxy-3-methyl-2-all-trans-octaprenyl-1,4-benzoquinol + a reduced electron acceptor + oxygen the ubiF mutant accumulates 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinone. The enzyme has not been characterized biochemically Escherichia coli an oxidized electron acceptor + 3-demethylubiquinol-8 + H2O
-
 ?

Subunits

EC Number Subunits Comment Organism
1.14.99.60 ? x * 42953, calculated from sequence Escherichia coli

Synonyms

EC Number Synonyms Comment Organism
1.14.99.60 ubiF
-
 Escherichia coli

pI Value

EC Number Organism Comment pI Value Maximum pI Value
1.14.99.60 Escherichia coli calculated from sequence
-
 6.64

General Information

EC Number General Information Comment Organism
1.14.99.60 malfunction the ubiF mutant shows poor growth on glucose and no growth on succinate, the ubiF mutant accumulates 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinone Escherichia coli
1.14.99.60 physiological function the enzyme catalyzes a reaction in the ubiquinone biosynthesis pathway Escherichia coli