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Literature summary extracted from

  • Kron, M.A.; Metwali, A.; Vodanovic-Jankovic, S.; Elliott, D.
    Nematode asparaginyl-tRNA synthetase resolves intestinal inflammation in mice with T-cell transfer colitis (2013), Clin. Vaccine Immunol., 20, 276-281.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
6.1.1.12
-
 Brugia malayi

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
6.1.1.12 cytoplasm
-
 Brugia malayi 5737
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
6.1.1.12 ATP + L-aspartate + tRNAAsp Brugia malayi
-
 AMP + diphosphate + L-aspartyl-tRNAAsp
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
6.1.1.12 Brugia malayi
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
6.1.1.12 magnesium sulfate precipitation, column chromatography, nickel affinity chromatography, and anion-exchange chromatography Brugia malayi

Source Tissue

EC Number Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6.1.1.12 ATP + L-aspartate + tRNAAsp
-
 Brugia malayi AMP + diphosphate + L-aspartyl-tRNAAsp
-
 ?

Synonyms

EC Number Synonyms Comment Organism
6.1.1.12 AsnRS
-
 Brugia malayi
6.1.1.12 Aspartyl-tRNA synthetase
-
 Brugia malayi

Cofactor

EC Number Cofactor Comment Organism Structure
6.1.1.12 ATP
-
 Brugia malayi

General Information

EC Number General Information Comment Organism
6.1.1.12 physiological function the enzyme induces an anti-inflammatory effect in mice with T-cell transfer colitis by interacting with interleukin-8 receptors Brugia malayi